Evidence map›Paper›PMID 31102055›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Cancer-related fatigue and biochemical parameters among cancer patients with different stages of sarcopenia.

Bangyan Wang, Sudip Thapa, Ting Zhou, Huiquan Liu, Lu Li, Guang Peng, Shiying Yu

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06255145 (Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06255145 nacompletednot on this mapstarted 2021, after this paper: background citation

Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals

TypeinterventionalSponsorPamukkale UniversityRan2021 to 2022Enrolled42ConditionsCerebrovascular Stroke, Body CompositionArmsBioelectrical Impedance Analysis
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Objective measurement of cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  12. Article
  13. Emerging markers of cancer cachexia and their relationship to sarcopenia.Journal of cancer research and clinical oncology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Absence of risk of sarcopenia protects cancer patients from fatigue.European journal of clinical nutrition · 2022
    Article
  19. Observational
  20. Awareness, perceptions and practices regarding cancer-related malnutrition and sarcopenia: a survey of cancer clinicians.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Bangyan WangCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.
Sudip ThapaCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.
Ting ZhouCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.
Huiquan LiuCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.
Lu LiCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China.
Guang PengDepartment of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shiying YuCancer Center of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, Hubei Province, People's Republic of China. syyu_tjh@163.com.ORCID http://orcid.org/0000-0003-3507-3464
Tongji Hospital · CNThe University of Texas MD Anderson Cancer Center · US

Funding

National Natural Science Foundation of China 81572961
6 · The paper itself

Abstract

purposeCancer-related fatigue (CRF) is a pervasive symptom experienced by cancer patients. Sarcopenia has been suggested as a treatment target of CRF. This study aims to assess the differences of CRF and biochemical markers among different stages of sarcopenia which remain poorly delineated.

methodsA total of 187 patients were included in this cross-sectional study. Based on muscle mass (skeletal muscle index, SMI), muscle strength (handgrip strength), and physical performance (SARC-F score), patients were divided into four groups (non-sarcopenia, pre-sarcopenia, sarcopenia, and severe sarcopenia). Cancer-related fatigue was measured by the Brief Fatigue Inventory (BFI). Biochemical markers were measured by routine blood tests.

resultsThe BFI score was significantly associated with sarcopenia stage (r=0.500; P<0.001). Cancer patients in severe sarcopenia group suffered from worse CRF than those in non-sarcopenia, pre-sarcopenia, and sarcopenia groups (P<0.001). In the multivariate linear regression model (R

conclusionsThe significantly increased occurrence and severity of CRF in cancer patients with sarcopenia suggest that sarcopenia may be a crucial target to improve the management of CRF. Circulating albumin and cholinesterase have the potential to predicting sarcopenia as biomarkers.

Indexed as

Cross-Sectional StudiesFatigueFemaleHumansMaleMiddle AgedNeoplasmsSarcopeniaAlbuminCancerCholinesteraseFatigueMuscleSarcopenia

Identifiers

PMID31102055
OpenAlexW2945135113

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.