ArticleClinical oral investigations2020
The mineralizing effect of zinc oxide-modified hydroxyapatite-based sealer on radicular dentin.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- Application of Coltosol F with a cotton-spacer technique for endodontic temporization: a clinical retrospective study.BMC oral health · 2026Article
- Morphological and physicochemical impact of an experimental epigallocatechin-3-gallate based gel on erosive dentin wear.European oral research · 2026Article
- Article
- Biomineralization-Inspired Anti-Caries Strategy Based on Multifunctional Nanogels as Mineral Feedstock Carriers.International journal of nanomedicine · 2023Article
- [Effect of nanohydroxyapatite on surface mineralization in acid-etched dentinal tubules and adsorption of lead ions].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveThe aim of this study was to evaluate the remineralization ability of three endodontic sealer materials at different root dentin regions. MATERIAL AND
methodsCervical, medial, and apical root dentin surfaces were treated with two experimental hydroxyapatite-based cements, containing sodium hydroxide (calcypatite) or zinc oxide (oxipatite); an epoxy resin-based canal sealer, AH Plus; and gutta-percha. Remineralization, at the inner and outer zones of dentin disk surfaces, was studied by nanohardness (Hi) and Raman analysis. Nanoroughness and collagen fibrils width measurements were performed. Numerical data, at 24 h or 12 m, were analyzed by ANOVA and Student-Newman-Keuls (p < 0.05).
resultsAt the outer and inner zones of the cervical dentin treated with oxipatite, the highest Hi after 12 m of immersion was achieved. The same group showed the highest intensity of phosphate peak, markers for calcification and crystallinity. Nanoroughness was lower and fibril diameter was higher at the inner zone of the dentin treated with oxipatite. Dentin mineralization occurred in every region of the root dentin treated with oxipatite and calcypatite, especially at the inner zone of the dentin after 12 m.
conclusionsOxipatite reinforced the inner root zone at any third of the radicular dentin, by increasing both nanohardness and remineralization. When using calcypatite, the highest nanohardness was found at the apical third of the inner root dentin, but the lowest mechanical performance was obtained at the cervical and the medial thirds of the roots. Therefore, application of oxipatite as sealing cement of root canals is recommended. CLINICAL RELEVANCE: Oxipatite, when used as an endodontic sealing material, strengthens radicular dentin.
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