Evidence map›Paper›PMID 31102039›Full record

ArticleMolecular imaging and biology2020

GABA

M Kessler, M Mamach, R Beutelmann, M Lukacevic, S Eilert, P Bascuñana, A Fasel, F M Bengel, J P Bankstahl, T L Ross and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Aging in the Primary Auditory Cortex.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Review
  3. Article
  4. Article
  5. Age-Related Deficits in Binaural Hearing: Contribution of Peripheral and Central Effects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

M KesslerDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Kessler.Mariella@mh-hannover.de.ORCID 0000-0002-7433-6805
M MamachDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
R BeutelmannDivision of Animal Physiology and Behaviour, Department for Neuroscience, School of Medicine and Health Sciences, University of Oldenburg, Carl von Ossietzky Str. 9-11, 26129, Oldenburg, Germany.
M LukacevicDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
S EilertDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
P BascuñanaDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
A FaselABX Advanced Biochemical Compounds GmbH, Heinrich-Glaeser-Strasse 10-14, 01454, Radeberg, Germany.
F M BengelDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
J P BankstahlDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
T L RossDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
G M KlumpCluster of Excellence Hearing4all, Hannover Medical School and University of Oldenburg, Hannover, Germany.
G BerdingDepartment of Nuclear Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Medizinische Hochschule Hannover · DECarl von Ossietzky Universität Oldenburg · DEABX-CRO Advanced Pharmaceutical Services (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePlastic changes in the central auditory system involving the GABAergic system accompany age-related hearing loss. Such processes can be investigated with positron emission tomography (PET) imaging using [ PROCEDURES: Sixty-minute list-mode PET acquisitions were performed in 9 young (range 5-6 months) and 11 old (range 39-42 months) gerbils, starting simultaneously with the injection of [

resultsBPnd differed significantly between models (p < 0.0005), showing the smallest mean difference between 2TCM as reference and SRTM as simplified procedure. SRTM revealed the lowest AIC values. Both volume of distribution (r

conclusionImaging of GABA

Indexed as

Positron-Emission TomographyAge FactorsAgingAnimalsAutoradiographyBrainBrain MappingFlumazenilFluorine RadioisotopesGerbillinaeKineticsRadiopharmaceuticalsReceptors, GABA-AFlumazenilFluorine-18Fluorine RadioisotopesRadiopharmaceuticalsReceptors, GABA-AAge-related hearing lossAgingAuditory systemBio-kinetic modelingFlumazenilGABAA-receptorInhibitory neurotransmitter system

Identifiers

PMID31102039
OpenAlexW2946669975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.