Evidence map›Paper›PMID 31101931›Full record

ArticleDiabetologia2019

CD40-targeted peptide proposed for type 1 diabetes therapy lacks relevant binding affinity to its cognate receptor.

Philippe P Pagni, Anitra Wolf, Mauro Lo Conte, Ronald Yeh, Guangsen Fu, Fa Liu, Matthias von Herrath, Ken Coppieters

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Diabetologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. CD40-targeting KGYYDiabetologia · 2019
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Philippe P PagniNovo Nordisk Research Center, Seattle, WA, USA.
Anitra WolfNovo Nordisk Research Center, Seattle, WA, USA.
Mauro Lo ConteNovo Nordisk Research Center, Seattle, WA, USA.
Ronald YehNovo Nordisk Research Center, Seattle, WA, USA.
Guangsen FuNovo Nordisk Research Center, Seattle, WA, USA.
Fa LiuNovo Nordisk Research Center, Seattle, WA, USA.
Matthias von HerrathNovo Nordisk Research Center, Seattle, WA, USA.
Ken CoppietersNovo Nordisk A/S Research Projects, Novo Nordisk Park, DK-2760, Måløv, Denmark. kncp@novonordisk.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 1AnimalsCD40 AntigensCD40 LigandMiceMice, Inbred NODPeptidesCD40 AntigensCD40 LigandPeptidesCD40CD40LType 1 diabetes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.