Evidence map›Paper›PMID 31101615›Full record

ArticleApplied and environmental microbiology2019

Ascomycete Aspergillus oryzae Is an Efficient Expression Host for Production of Basidiomycete Terpenes by Using Genomic DNA Sequences.

Shota Nagamine, Chengwei Liu, Jumpei Nishishita, Takuto Kozaki, Kaho Sogahata, Yoshiro Sato, Atsushi Minami, Taro Ozaki, Claudia Schmidt-Dannert, Jun-Ichi Maruyama and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Metabolic reprogramming of abscisic acid-producing strainSynthetic and systems biotechnology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome.Chembiochem : a European journal of chemical biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Secondary Metabolites ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  13. Article
  14. Synthetic Biology Tools for EngineeringJournal of fungi (Basel, Switzerland) · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Biosynthesis of Sesquiterpenes in Basidiomycetes: A Review.Journal of fungi (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Shota NagamineDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Chengwei LiuDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Jumpei NishishitaDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Takuto KozakiDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Kaho SogahataDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Yoshiro SatoDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Atsushi MinamiDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan aminami@sci.hokudai.ac.jp hoik@sci.hokudai.ac.jp.
Taro OzakiDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan.
Claudia Schmidt-DannertDepartment of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, St. Paul, Minnesota, USA.
Jun-Ichi MaruyamaDepartment of Biotechnology, The University of Tokyo, Tokyo, Japan.
Hideaki OikawaDepartment of Chemistry, Faculty of Science, Hokkaido University, Sapporo, Japan aminami@sci.hokudai.ac.jp hoik@sci.hokudai.ac.jp.
Hokkaido University · JPThe University of Tokyo · JPUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basidiomycete fungi are an attractive resource for biologically active natural products for use in pharmaceutically relevant compounds. Recently, genome projects on mushroom fungi have provided a great deal of biosynthetic gene cluster information. However, functional analyses of the gene clusters for natural products were largely unexplored because of the difficulty of cDNA preparation and lack of gene manipulation tools for basidiomycete fungi. To develop a versatile host for basidiomycete genes, we examined gene expression using genomic DNA sequences in the robust ascomycete host

Indexed as

BasidiomycotaGenes, FungalAlkyl and Aryl TransferasesAspergillus oryzaeEurotialesMicroorganisms, Genetically-ModifiedMultigene FamilyTerpenesAlkyl and Aryl TransferasesTerpenesterpene synthaseAspergillus oryzaebasidiomycete fungiheterologous expressionterpenesterpene synthase

Identifiers

PMID31101615
PMCPMC6643257
OpenAlexW2946612481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.