ReviewSeizure2020
DC shifts, high frequency oscillations, ripples and fast ripples in relation to the seizure onset zone.
Review in Seizure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Robust time delay estimation for measurement of ictal EEG traveling waves.Journal of neural engineering · 2026Article
- An artefact-resilient wide bandwidth bidirectional graphene neural interface.Nature communications · 2026Article
- Multimodal quantitative analysis guides precise preoperative localization of epilepsy.Journal of neurology · 2025Review
- Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats.Cell reports · 2025Article
- Rodent and human seizures demonstrate a dynamic interplay with spreading depolarizations.Neurobiology of disease · 2025Article
- Deep learning in intracranial EEG for seizure detection: advances, challenges, and clinical applications.Frontiers in neuroscience · 2025Review
- Integrating Spatial-Temporal Channel Reliability with AI for Robust High-Frequency Oscillation Detection in Intracranial EEG.International IEEE/EMBS Conference on Neural Engineering : [proceedings]. International IEEE EMBS Conference on Neural Engineering · 2025Article
- Innovating beyond electrophysiology through multimodal neural interfaces.Nature reviews electrical engineering · 2025Article
- Long-Term Ambulatory Intracranial EEG.Stereotactic and functional neurosurgery · 2025Review
- Using high-frequency oscillations from brief intraoperative neural recordings to predict the seizure onset zone.Communications medicine · 2024Article
- Connectivity of high-frequency bursts as SOZ localization biomarker.Frontiers in network physiology · 2024Article
- A Review of EEG-based Localization of Epileptic Seizure Foci: Common Points with Multimodal Fusion of Brain Data.Journal of medical signals and sensors · 2024Review
- Optimization of ictal aborting stimulation using the dynamotype taxonomy.Journal of computational neuroscience · 2023Article
- Quantitative approaches to guide epilepsy surgery from intracranial EEG.Brain : a journal of neurology · 2023Article
- A sparse representation strategy to eliminate pseudo-HFO events from intracranial EEG for seizure onset zone localization.Journal of neural engineering · 2022Article
- Digital reconstruction of infraslow activity in human intracranial ictal recordings using a deconvolution-based inverse filter.Scientific reports · 2022Article
- High-Frequency Oscillations and Epileptogenic Network.Current neuropharmacology · 2022Article
- Elimination of pseudo-HFOs in iEEG using sparse representation and Random Forest classifier.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2022Article
- The advantages of mapping slow brain potentials using DC-coupled graphene micro-transistors: Clinical and translational applications.Clinical and translational medicine · 2022Article
- Full-bandwidth electrophysiology of seizures and epileptiform activity enabled by flexible graphene microtransistor depth neural probes.Nature nanotechnology · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Efforts to improve epilepsy surgery outcomes have led to increased interest in the study of electroencephalographic oscillations outside the conventional EEG bands. These include fast activity above the gamma band, known as high frequency oscillations (HFOs), and infraslow activity (ISA) below the delta band, sometimes referred to as direct current (DC) or ictal baseline shifts (IBS). HFOs in particular have been extensively studied as potential biomarkers for epileptogenic tissue in light of evidence showing that resection of brain tissue containing HFOs is associated with good surgical outcomes. Not all HFOs are conclusively pathological, however, as they can be recorded in nonepileptic tissue and induced by cognitive, visual, or motor tasks. Consequently, efforts to distinguish between pathological and physiological HFOs have identified several traits specific to pathological HFOs, such as coupling with interictal spikes, association with delta waves, and stereotypical morphologies. On the opposite end of the EEG spectrum, sub-delta oscillations have been shown to co-localize with the seizure onset zones (SOZ) and appear in a narrower spatial distribution than activity in the conventional EEG frequency bands. In this report, we review studies that implicate HFOs and ISA in ictogenesis and discuss current limitations such as inter-observer variability and poor standardization of recording techniques. Furthermore, we propose that HFOs and ISA should be analyzed in addition to activity in the conventional EEG band during intracranial presurgical EEG monitoring to identify the best possible surgical margin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.