ArticleBMC cancer2019
Prevalence and factors associated with major depressive disorder in children and adolescents at the Uganda Cancer Institute.
Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
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- Abnormal amplitude of low-frequency fluctuation values as a neuroimaging biomarker for major depressive disorder with suicidal attempts in adolescents: A resting-state fMRI and support vector machine analysis.Frontiers in psychology · 2023Article
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- Correlation between dietary score and depression in cancer patients: Data from the 2005-2018 National Health and Nutrition Examination Surveys.Frontiers in psychology · 2022Article
- Influencing factors of depressive symptoms in patients with malignant tumour.The Journal of international medical research · 2021Article
- A Half Century of Research on Childhood and Adolescent Depression: Science Mapping the Literature, 1970 to 2019.International journal of environmental research and public health · 2021Article
- Prevalence and Determinants of Depression Among Adolescent Girls and Young Women at Risk of HIV in Urban Slums of Kampala.Inquiry : a journal of medical care organization, provision and financingArticle
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4 authors at 2 institutions in 1 country.
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Abstract
backgroundThe prevalence and factors associated with major depressive disorder (MDD) among adults with cancer have been documented in the scientific literature. However, this data is limited among children and adolescents with cancer; especially in low resource settings such as Uganda. We assessed the prevalence and factors associated with MDD in children and adolescents attending the Uganda cancer institute out-patient clinic.
methodsThis was a cross-sectional study in which three hundred and fifty-two children and adolescents with any cancer diagnosis were screened for depression using the Child Depression Inventory (CDI) and evaluated with the mini neuropsychiatric interview for children and adolescents (MINI-KID). Associated factors were assessed using a standardized questionnaire that assessed child and caregiver demographic and psychosocial characteristics. Multiple logistic regression models were used to assess factors independently associated with MDD.
resultsOf the 352 children and adolescents recruited in the study 134(38%) scored above a cut-off point of 13 on the CDI indicating significant depression symptoms. However, 91(26%) met criteria for MDD. The majority of those with MDD (n = 59 64.8%) had CDI scores of 13-19 indicating mild depression, 30(33%) had scores of 20-25 indicating moderate depression and 2(2.2%) had scores of 25 and above indicating severe depression. Protective factors against MDD were having a special person in the respondent's life (p = 0.002) and using self-distraction as a coping method (p = < 0.001). Risk factors were being an adolescent(p = < 0.001).
conclusionThe prevalence of MDD is substantial in children and adolescents with cancer in Uganda. Given that the majority had a mild-moderate depression, there is an urgent need to integrate psychotherapy-the first-line treatment for depression into the routine care of children and adolescents with cancer.
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