ArticleEnvironmental health and preventive medicine2019
Exposure profile of mercury, lead, cadmium, arsenic, antimony, copper, selenium and zinc in maternal blood, cord blood and placenta: the Tohoku Study of Child Development in Japan.
Article in Environmental health and preventive medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 91 citations in OpenAlex.
- Toxic Trace Element Levels in Maternal and Cord Blood Worldwide and Their Impact on Pregnancy: A Narrative Review.Journal of xenobiotics · 2026Review
- Hair metal concentrations in a mother-newborn population from a polluted megacity: an indicator of prenatal metal exposure.Journal of exposure science & environmental epidemiology · 2026Article
- Environmental Arsenic Contamination and Human Health Risk Assessment in the Kosi Plain Region of Bihar, India.Biological trace element research · 2026Article
- Maternal-Fetal Exposure to Oncoelements and Their Oxidative and Epigenetic Impact on Pregnancy Outcomes.International journal of molecular sciences · 2026Review
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- Article
- Perinatal Exposure to Trace Elements: The Dubious Culprit of Autistic Spectrum Disorder in Children.Current pediatric reviews · 2024Review
- Concentrations of potentially toxic metals and trace elements in pregnant women and association with birth outcomes: A cross-sectional study in Malawi.PLOS global public health · 2024Article
- Biomonitoring of inorganic arsenic species in pregnancy.Journal of exposure science & environmental epidemiology · 2023Review
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- Content of selected heavy metals in the umbilical cord blood and anthropometric data of mothers and newborns in Poland: preliminary data.Scientific reports · 2023Article
- Placental Barrier on Cadmium Transfer from Mother to Fetus in Related to Pregnancy Complications.International journal of women's health · 2023Article
- Environmental toxicants and placental function.Best practice & research. Clinical obstetrics & gynaecology · 2022Review
- Examination of Trace Metals and Their Potential Transplacental Transfer in Pregnancy.International journal of molecular sciences · 2022Article
- Analysis of essential, toxic, rare earth, and noble elements in maternal and umbilical cord blood.Environmental science and pollution research international · 2022Article
- Global DNA Methylation in Cord Blood as a Biomarker for Prenatal Lead and Antimony Exposures.Toxics · 2022Article
- Maternal Blood Levels of Toxic and Essential Elements and Birth Outcomes in Argentina: The EMASAR Study.International journal of environmental research and public health · 2022Article
- Selected Metal Concentration in Maternal and Cord Blood.International journal of environmental research and public health · 2021Article
- Assessing reference levels of nickel and chromium in cord blood, maternal blood and placenta specimens from Ankara, TurkeyJournal of the Turkish German Gynecological Association · 2021Article
- Maternal seafood intake during pregnancy, prenatal mercury exposure and child body mass index trajectories up to 8 years.International journal of epidemiology · 2021Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe effects of prenatal exposure to toxic elements on birth outcomes and child development have been an area of concern. This study aimed to assess the profile of prenatal exposure to toxic elements, arsenic (As), bismuth (Bi), cadmium (Cd), mercury (total mercury (THg), methylmercury (MHg), inorganic mercury (IHg)), lead (Pb), antimony (Sb) and tin (Sn), and essential trace elements, copper (Cu), selenium (Se) and zinc (Zn), using the maternal blood, cord blood and placenta in the Tohoku Study of Child Development of Japan (N = 594-650).
methodsInductively coupled plasma mass spectrometry was used to determine the concentrations of these elements (except mercury). Levels of THg and MeHg were measured using cold vapour atomic absorption spectrophotometry and a gas chromatograph-electron capture detector, respectively.
resultsMedian concentrations (25th-75th) of As, Cd, Pb, Sb, Sn and THg in the maternal blood were 4.06 (2.68-6.81), 1.18 (0.74-1.79), 10.8 (8.65-13.5), 0.2 (0.06-0.40) and 0.2 (0.1-0.38) ng mL
conclusionsTHg and Sb levels in the cord blood were twofold higher than those in the maternal blood. Cord blood to maternal blood ratios for As, Cd and Sb widely varied between individuals. To understand the effects of prenatal exposure, further research regarding the variations of placental transfer of elements is necessary.
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