Evidence map›Paper›PMID 31100935›Full record

ArticleJournal of clinical medicine2019

Expression of Glypican 3 is an Independent Prognostic Biomarker in Primary Gastro-Esophageal Adenocarcinoma and Corresponding Serum Exosomes.

Mohammad Rahbari, Mathieu Pecqueux, Daniela Aust, Holger Stephan, Oliver Tiebel, Antonios Chatzigeorgiou, Torsten Tonn, Franziska Baenke, Venkatesh Rao, Nicole Ziegler and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Mohammad RahbariDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Mohammad.Rahbari@uniklinikum-dresden.de.
Mathieu PecqueuxDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Mathieu.Pecqueux@uniklinikum-dresden.de.
Daniela AustInstitute for Pathology, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Daniela.Aust@uniklinikum-dresden.de.
Holger StephanHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Bautzner Landstrasse 400, D-01328 Dresden, Germany. h.stephan@hzdr.de.
Oliver TiebelInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. oliver.tiebel@uniklinikum-dresden.de.
Antonios ChatzigeorgiouInstitute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. antonios.chatzigeorgiou@uniklinikum-dresden.de.
Torsten TonnInstitute for Transfusion Medicine, German Red Cross Blood Donation Service North-East, D-01307 Dresden, Germany. t.tonn@blutspende.de.
Franziska BaenkeDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Franziska.Baenke@uniklinikum-dresden.de.
Venkatesh RaoDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Rao.Venkatesh@uniklinikum-dresden.de.
Nicole ZieglerDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Nicole.Ziegler@uniklinikum-dresden.de.
Helena GreifDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Helena.Greif@uniklinikum-dresden.de.
Kuailu LinDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Kuailu.Lin@uniklinikum-dresden.de.
Juergen WeitzDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Juergen.Weitz@uniklinikum-dresden.de.
Nuh Nabi RahbariDepartment of Surgery, University Medicine Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, D-68167 Mannheim, Germany. Nuh.Rahbari@umm.de.
Christoph KahlertDepartment of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, D-01307 Dresden, Germany. Christoph.Kahlert@uniklinikum-dresden.de.
University Hospital Carl Gustav Carus · DEGerman Cancer Research Center · DEGerman Red Cross · DEHeidelberg University · DEHelmholtz-Zentrum Dresden-Rossendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are nano-sized membranous vesicles of endosomal origin that carry nucleic acids, lipids and proteins. The cargo of exosomes is cell origin specific and the release of these exosomes and uptake by an acceptor cell is seen as a vital element of cell-cell communication. Here, we sought to investigate the diagnostic and prognostic value of the expression of glypican 3 (

Indexed as

antibody secreting cellbiomarkerbreast cancerimmune profileimmunotherapylymph nodemicroarraytumor antigen

Identifiers

PMID31100935
PMCPMC6572603
OpenAlexW2946386246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.