SynthesisNutrients2019
Iron Deficiency and Iron Homeostasis in Low Birth Weight Preterm Infants: A Systematic Review.
Synthesis in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- [Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Guideline
- A systematic review and meta-analysis of the prevalence and associated factors of iron-deficiency anemia among Chinese children under 6 years of age.Frontiers in pediatrics · 2025Pooled it
- Beyond the Mind-Serum Trace Element Levels in Schizophrenic Patients: A Systematic Review.International journal of molecular sciences · 2020Pooled it
- Preterm Infants on Early Solid Foods and Iron Status in the First Year of Life-A Secondary Outcome Analysis of a Randomized Controlled Trial.Nutrients · 2022Trial
- Article
- Identification and Assessment of Systematic Reviews for Evidence-Based Guideline Recommendations on Follow-Up of Preterm Born Children: A Mapping Review.Acta paediatrica (Oslo, Norway : 1992) · 2026Review
- Prevalence and Predictors of Iron Deficiency at Hospital Discharge in Very-Low-Birth-Weight Infants: A Prospective Single-Center Observational Study Using RET-He and Serum Ferritin.Children (Basel, Switzerland) · 2026Article
- Longitudinal Plasma Ferritin in the First Year of Life in Relation to Maternal Status, Birth Characteristics, and Breastfeeding.Nutrients · 2026Observational
- Antenatal maternal anaemia and infant brain structure: high-field (3 T) and ultra-low-field (64 mT) MRI findings from South Africa.Brain communications · 2026Article
- Red Blood Cell Transfusion and Risk of Iron Overload in Preterm Infants: A Prospective Study on Serum Ferritin and Hepcidin.Neonatology · 2026Article
- Is Iron Supplementation Associated with Infant Mortality in Sub-Saharan Africa and Does Birth Weight Modify These Associations?Nutrients · 2025Article
- Phlebotomy-induced anemia reduces oxygen-induced retinopathy severity and dampens retinal developmental transcriptomic pathways in rats.Pediatric research · 2025Article
- Altered heme metabolism and hemoglobin concentration due to empirical antibiotics-induced gut dysbiosis in preterm infants.Computational and structural biotechnology journal · 2025Article
- An analysis on role of iron deficiency in febrile seizure among children in 6 months to 5 years: A case-control study.Journal of family medicine and primary care · 2024Article
- The effect of iron supplementation in preterm infants at different gestational ages.BMC pediatrics · 2024Article
- Hyperferritinemia among very-low-birthweight infants in Thailand: a prospective cohort study.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- The Early Hematological Profile and Its Variations: A Useful Tool in the Prediction of Intraventricular Hemorrhage in Extremely Preterm Infants.Medicina (Kaunas, Lithuania) · 2024Article
- Article
- Iron Intake and Human Health.Nutrients · 2024Article
- The Relationship Between Iron and Zinc Deficiency and Aphthous Stomatitis: A Systematic Review and Meta-Analysis.Advanced biomedical research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Iron is an essential micronutrient that is involved in many functions in humans, as it plays a critical role in the growth and development of the central nervous system, among others. Premature and low birth weight infants have higher iron requirements due to increased postnatal growth compared to that of term infants and are, therefore, susceptible to a higher risk of developing iron deficiency or iron deficiency anemia. Notwithstanding, excess iron could affect organ development during the postnatal period, particularly in premature infants that have an immature and undeveloped antioxidant system. It is important, therefore, to perform a review and analyze the effects of iron status on the growth of premature infants. This is a transversal descriptive study of retrieved reports in the scientific literature by a systematic technique. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were adapted for the review strategy. The inclusion criteria for the studies were made using the PICO (population, intervention, comparison, outcome) model. Consequently, the systematic reviews that included studies published between 2008-2018 were evaluated based on the impact of iron status on parameters of growth and development in preterm infants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.