Evidence map›Paper›PMID 31100703›Full record

ArticleDNA repair2019

Characterization of rare NEIL1 variants found in East Asian populations.

Irina G Minko, Vladimir L Vartanian, Naoto N Tozaki, Oskar K Linde, Pawel Jaruga, Sanem Hosbas Coskun, Erdem Coskun, Chunfeng Qu, Huan He, Chungui Xu and 8 more

Open access · greenAbstract read
In one paragraph

Article in DNA repair, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Aflatoxin BEnvironmental and molecular mutagenesis · 2025
    Article
  4. Review
  5. Article
  6. Research progress on the role of the NEIL family in cancer.Frontiers in cell and developmental biology · 2025
    Review
  7. Article
  8. Frequencies and spectra of aflatoxin BNAR molecular medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action.International journal of environmental research and public health · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 2 countries.

Irina G MinkoOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States.
Vladimir L VartanianOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States.
Naoto N TozakiOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States.
Oskar K LindeOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States.
Pawel JarugaBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, United States.
Sanem Hosbas CoskunBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, United States.
Erdem CoskunBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, United States.
Chunfeng QuState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Huan HeState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Chungui XuState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Taoyang ChenQidong Liver Cancer Institute & Qidong People's Hospital, Qidong, 226200, Jiangsu Province, China.
Qianqian SongState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Yuchen JiaoState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China.
Michael P StoneDepartment of Chemistry, Vanderbilt University, Nashville, TN, 37235, United States.
Martin EgliDepartment of Biochemistry, Vanderbilt University, Nashville, TN, 37232, United States.
Miral DizdarogluBiomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, United States.
Amanda K McCulloughOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, 97239, United States.
R Stephen LloydOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, 97239, United States; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, 97239, United States; Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR, 97239, United States. Electronic address: lloydst@ohsu.edu.
Oregon Health & Science University · USChinese Academy of Medical Sciences & Peking Union Medical College · CNMaterial Measurement Laboratory · USNational Institute of Standards and Technology · USVanderbilt University · USQidong Liver Cancer Prevention Research · CN

Funding

Synthetic Approaches to Carcinogen-Linked OligonucleotidesP01CA160032 · NCI · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2012 to 2022
$14.0M
DNA Adduct-Induced MutagenesisR01CA055678 · NCI · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 1992 to 2016
$4.0M
DNA Adduct-Induced MutagenesisR01ES029357 · NIEHS · VANDERBILT UNIVERSITY · PI STONE, MICHAEL P · 2018 to 2022
$2.6M
The roles of BER and TLS in limiting aflatoxin-induced carcinogenesisR56ES027632 · NIEHS · OREGON HEALTH & SCIENCE UNIVERSITY · PI LLOYD, R. STEPHEN · 2017 to 2017
$308k
NCI NIH HHS P01 CA160032NCI NIH HHS R01 CA055678NIEHS NIH HHS R01 ES029357NIEHS NIH HHS R56 ES027632
6 · The paper itself

Abstract

The combination of chronic dietary exposure to the fungal toxin, aflatoxin B

Indexed as

DNA RepairMutationPolymorphism, Single NucleotideAsian PeopleDNA AdductsDNA GlycosylasesEnzyme StabilityEscherichia coliHumansProtein DomainsSubstrate SpecificityDNA AdductsDNA GlycosylasesNEIL1 protein, humanAflatoxinBase excision repairFormamidopyrimidinesHepatocellular carcinomaThymine glycol

Identifiers

PMID31100703
PMCPMC6677271
OpenAlexW2943220352

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.