Evidence map›Paper›PMID 31100023›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Scleraxis genes are required for normal musculoskeletal development and for rib growth and mineralization in zebrafish.

Erika Kague, Simon M Hughes, Elizabeth A Lawrence, Stephen Cross, Elizabeth Martin-Silverstone, Chrissy L Hammond, Yaniv Hinits

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
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  7. The Mutation ofInternational journal of molecular sciences · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Animal models of tendon calcification: Past, present, and future.Animal models and experimental medicine · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Zebrafish crocc2 mutants exhibit divergent craniofacial shape, misregulated variability, and aberrant cartilage morphogenesis.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Single-cell transcriptomes andNational science review · 2022
    Review
  20. Coordinated patterning of zebrafish caudal fin symmetry by a central and two peripheral organizers.Developmental dynamics : an official publication of the American Association of Anatomists · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Erika KagueDepartment of Physiology, Pharmacology, and Neuroscience, Medical Sciences, University of Bristol, Bristol, United Kingdom.
Simon M HughesRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
Elizabeth A LawrenceDepartment of Physiology, Pharmacology, and Neuroscience, Medical Sciences, University of Bristol, Bristol, United Kingdom.
Stephen CrossDepartment of Physiology, Pharmacology, and Neuroscience, Medical Sciences, University of Bristol, Bristol, United Kingdom.
Elizabeth Martin-SilverstoneDepartment of Physiology, Pharmacology, and Neuroscience, Medical Sciences, University of Bristol, Bristol, United Kingdom.
Chrissy L HammondDepartment of Physiology, Pharmacology, and Neuroscience, Medical Sciences, University of Bristol, Bristol, United Kingdom.
Yaniv HinitsRandall Centre for Cell and Molecular Biophysics, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
University of Bristol · GBKing's College London · GB

Funding

Arthritis Research UK 19476Arthritis Research UK 21121Arthritis Research UK 21937British Heart Foundation PG/14/12/30664Medical Research Council G1001029Medical Research Council MR/N021231/1Versus Arthritis 19476Versus Arthritis 21937Wellcome Trust
6 · The paper itself

Abstract

Tendons are an essential part of the musculoskeletal system, connecting muscle and skeletal elements to enable force generation. The transcription factor scleraxis marks vertebrate tendons from early specification.

Indexed as

AnimalsAnimals, Genetically ModifiedBasic Helix-Loop-Helix ProteinsBone DevelopmentCalcification, PhysiologicGene Expression Regulation, DevelopmentalMusculoskeletal DevelopmentMutationRibsTendonsZebrafishZebrafish ProteinsBasic Helix-Loop-Helix ProteinsZebrafish Proteinscraniofacialmuscleribstendonzebrafish

Identifiers

PMID31100023
PMCPMC6662971
OpenAlexW2939862001

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.