Evidence map›Paper›PMID 31099916›Full record

Observational studyJournal of the European Academy of Dermatology and Venereology : JEADV2020

A retrospective analysis omalizumab treatment patterns in patients with chronic spontaneous urticaria: a real-world study in Belgium.

H Lapeere, M Baeck, A Stockman, V Sabato, M Grosber, M Moutschen, J Lambert, L Vandebuerie, L de Montjoye, H Rabijns and 2 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of the European Academy of Dermatology and Venereology : JEADV, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. [In vitro study on the individual binding ability of omalizumab with free IgE].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

H LapeereDepartment of Dermatology, Ghent University Hospital, Gent, Belgium.
M BaeckDepartment of Dermatology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
A StockmanDepartment of Dermatology, AZ Delta Campus Rembert Torhout, Torhout, Belgium.
V SabatoDepartment of Immunology-Allergology-Rheumatology, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
M GrosberDepartment of Dermatology, Universitair Ziekenhuis Brussel, Brussels, Belgium.
M MoutschenService Infectious Diseases and General Internal Medicine, CHU Liège, Liège, Belgium.
J LambertDepartment of Dermatology University Hospital Antwerp, University of Antwerp, Antwerp, Belgium.
L VandebuerieGroepspraktijk Dermatologie Roeselare, Roeselare, Belgium.
L de MontjoyeDepartment of Dermatology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.ORCID https://orcid.org/0000-0003-0673-0728
H RabijnsN.V. Novartis Pharma S.A., Vilvoorde, Belgium.
K AllewaertN.V. Novartis Pharma S.A., Vilvoorde, Belgium.
R SchrijversLaboratory of Clinical Immunology, KU Leuven Department of Microbiology and Immunology, Leuven, Belgium.

Funding

N.V. Novartis Pharma S.A.
6 · The paper itself

Abstract

backgroundChronic spontaneous urticaria (CSU) is characterized by the repeated occurrence of persistent hives and/or angioedema for ≥6 weeks, without specific external stimuli. H

objectiveTo collect real-world clinical data on omalizumab treatment in adults with CSU in Belgium.

methodsThis was an observational, retrospective chart review of adults with CSU, who initiated omalizumab treatment between August 2014 and December 2016 (maximum 28 months follow-up).

resultsIn total, 235 patients were included (median time from symptom onset to diagnosis, 5.4 months; median time from diagnosis to commencing omalizumab, 6.7 months). Treatments used before/after commencing omalizumab did not always adhere to guidelines; many patients (26.4%/11.1%) received first-generation H

conclusionsThis study revealed that patients initiated on omalizumab in Belgium had severe CSU at baseline, and showed substantial improvements after 1 month of treatment. Greater adherence to the prescription of guideline-recommended medications is needed for the treatment of CSU.

Indexed as

AdultAnti-Allergic AgentsBelgiumChronic UrticariaDrug Administration ScheduleFemaleHistamine AntagonistsHumansMaleMedication AdherenceMiddle AgedOmalizumabRetrospective StudiesTreatment OutcomeAnti-Allergic AgentsHistamine AntagonistsOmalizumab

Identifiers

PMID31099916
PMCPMC7003755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.