ArticleJournal of medical Internet research2019
Secure and Scalable mHealth Data Management Using Blockchain Combined With Client Hashchain: System Design and Validation.
Article in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Applications of Blockchain in the Medical Field: Narrative Review.Journal of medical Internet research · 2021Pooled it
- The Current State of Research, Challenges, and Future Research Directions of Blockchain Technology in Patient Care: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Blockchain for Digital Health Governance: Evidence Gap Map and Scoping Review.Journal of medical Internet research · 2026Article
- Blockchain Technology to Enhance Clinical Data Management in Healthcare: A Systematic Literature Review.Blockchain in healthcare today · 2026Review
- Blockchain Technology in Digital Health and Medical Technologies.Blockchain in healthcare today · 2025Article
- Review
- Blockchain: What is the use case for physicians in 2024? A rapid review of the literature.Future healthcare journal · 2024Review
- A systematic review of privacy-preserving methods deployed with blockchain and federated learning for the telemedicine.Healthcare analytics (New York, N.Y.) · 2023Review
- Digital health, digital medicine, and digital therapeutics in cardiology: current evidence and future perspective in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Is blockchain ready for orthopaedics? A systematic review.Journal of clinical orthopaedics and trauma · 2021Review
- Smart Decentralization of Personal Health Records with Physician Apps and Helper Agents on Blockchain: Platform Design and Implementation Study.JMIR medical informatics · 2021Article
- Determining the Intellectual Structure and Academic Trends of Smart Home Health Care Research: Coword and Topic Analyses.Journal of medical Internet research · 2021Review
- ACTION-EHR: Patient-Centric Blockchain-Based Electronic Health Record Data Management for Cancer Care.Journal of medical Internet research · 2020Article
- Blockchain in Health Care: Hope or Hype?Journal of medical Internet research · 2020Article
- Data Validation and Verification Using Blockchain in a Clinical Trial for Breast Cancer: Regulatory Sandbox.Journal of medical Internet research · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBlockchain is emerging as an innovative technology for secure data management in many areas, including medical practice. A distributed blockchain network is tolerant against network fault, and the registered data are resistant to tampering and revision. The technology has a high affinity with digital medicine like mobile health (mHealth) and provides reliability to the medical data without labor-intensive third-party contributions. On the other hand, the reliability of the medical data is not insured before registration to the blockchain network. Furthermore, there are issues with regard to how the clients' mobile devices should be dealt with and authenticated in the blockchain network in order to avoid impersonation.
objectiveThe aim of the study was to design and validate an mHealth system that enables the compatibility of the security and scalability of the medical data using blockchain technology.
methodsWe designed an mHealth system that sends medical data to the blockchain network via relay servers. The architecture provides scalability and convenience of operation of the system. In order to ensure the reliability of the data from clients' mobile devices, hash values with chain structure (client hashchain) were calculated in the clients' devices and the results were registered on the blockchain network.
resultsThe system was applied and deployed in mHealth for insomnia treatment. Clinical trials for mHealth were conducted with insomnia patients. Medical data of the recruited patients were successfully registered with the blockchain network via relay servers along with the hashchain calculated on the clients' mobile devices. The correctness of the data was validated by identifying illegal data, which were made by simulating fraudulent access.
conclusionsOur proposed mHealth system, blockchain combined with client hashchain, ensures compatibility of security and scalability in the data management of mHealth medical practice.
trial registrationUMIN Clinical Trials Registry UMIN000032951; https://upload.umin.ac.jp/cgi-open- bin/ctr_e/ctr_view.cgi?recptno=R000037564 (Archived by WebCite at http://www.webcitation.org/78HP5iFIw).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.