Evidence map›Paper›PMID 31099327›Full record

SynthesisInfection control and hospital epidemiology2019

Association between universal gloving and healthcare-associated infections: A systematic literature review and meta-analysis.

Nai-Chung N Chang, Ashley E Kates, Melissa A Ward, Elizabeth J Kiscaden, Heather Schacht Reisinger, Eli N Perencevich, Marin L Schweizer, CDC Prevention Epicenters Program

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Infection control and hospital epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nai-Chung N ChangDepartment of Epidemiology, College of Public Health,University of Iowa, Iowa City,Iowa.
Ashley E KatesDivision of Infectious Disease, Department of Medicine, School of Medicine and Public Health,University of Wisconsin-Madison,Madison, Wisconsin.
Melissa A WardDepartment of Internal Medicine, Carver College of Medicine,University of Iowa,Iowa City, Iowa.
Elizabeth J KiscadenHardin Library for the Health Sciences,University of Iowa,Iowa City, Iowa.
Heather Schacht ReisingerIowa City Veterans Affairs (VA) Health Care System, Center for Comprehensive Access & Delivery Research and Evaluation (CADRE), Iowa City,Iowa.
Eli N PerencevichIowa City Veterans Affairs (VA) Health Care System, Center for Comprehensive Access & Delivery Research and Evaluation (CADRE), Iowa City,Iowa.
Marin L SchweizerDepartment of Epidemiology, College of Public Health,University of Iowa, Iowa City,Iowa.ORCID 0000-0002-3604-0093
CDC Prevention Epicenters Program

Funding

HSRD VA CDP 13-004NCEZID CDC HHS U54 CK000448
6 · The paper itself

Abstract

objectiveHealthcare-associated infections (HAIs) are a significant burden on healthcare facilities. Universal gloving is a horizontal intervention to prevent transmission of pathogens that cause HAI. In this meta-analysis, we aimed to identify whether implementation of universal gloving is associated with decreased incidence of HAI in clinical settings.

methodsA systematic literature search was conducted to find all relevant publications using search terms for universal gloving and HAIs. Pooled incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were calculated using random effects models. Heterogeneity was evaluated using the Woolf test and the I2 test.

resultsIn total, 8 studies were included. These studies were moderately to substantially heterogeneous (I2 = 59%) and had varied results. Stratified analyses showed a nonsignificant association between universal gloving and incidence of methicillin-resistant Staphylococcus aureus (MRSA; pooled IRR, 0.94; 95% CI, 0.79-1.11) and vancomycin-resistant enterococci (VRE; pooled IRR, 0.94; 95% CI, 0.69-1.28). Studies that implemented universal gloving alone showed a significant association with decreased incidence of HAI (IRR, 0.77; 95% CI, 0.67-0.89), but studies implementing universal gloving as part of intervention bundles showed no significant association with incidence of HAI (IRR, 0.95; 95% CI, 0.86-1.05).

conclusionsUniversal gloving may be associated with a small protective effect against HAI. Despite limited data, universal gloving may be considered in high-risk settings, such as pediatric intensive care units. Further research should be performed to determine the effects of universal gloving on a broader range of pathogens, including gram-negative pathogens.

Indexed as

Cross InfectionGloves, ProtectiveGram-Positive Bacterial InfectionsHumansInfection ControlIntensive Care Units, PediatricMethicillin-Resistant Staphylococcus aureusRandomized Controlled Trials as TopicStaphylococcal InfectionsVancomycin-Resistant Enterococci

Identifiers

PMID31099327
PMCPMC12459995

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.