Evidence map›Paper›PMID 31099303›Full record

ArticlePulmonary circulation

United States Pulmonary Hypertension Scientific Registry (USPHSR): rationale, design, and clinical implications.

C Gregory Elliott, Eric D Austin, David Badesch, Jessica Badlam, Raymond L Benza, Wendy K Chung, Harrison W Farber, Kathy Feldkircher, Adaani E Frost, Abby D Poms and 4 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 1 country.

C Gregory Elliott1 Intermountain Medical Center Department of Medicine and the University of Utah, Pulmonary Division, Salt Lake City, UT, USA.
Eric D Austin2 Vanderbilt University Medical Center Department of Pediatrics, Nashville, TN, USA.
David Badesch3 University of Colorado, Denver, CO, USA.
Jessica Badlam4 University of Vermont, Burlington, VT, USA.
Raymond L Benza5 Allegheny General Hospital, Pittsburgh, PA, USA.
Wendy K Chung6 Columbia University Medical Center, New York, NY, USA.
Harrison W Farber7 Tufts University School of Medicine, Boston, MA, USA.
Kathy Feldkircher8 E Squared Trials and Registries, Inc., Half Moon Bay, CA, USA.
Adaani E Frost9 Houston Methodist Hospital Lung Center, Houston, TX, USA.
Abby D Poms9 Houston Methodist Hospital Lung Center, Houston, TX, USA.
Katie A Lutz10 Division of Human Genetics, Cincinnati Children's Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Michael W Pauciulo10 Division of Human Genetics, Cincinnati Children's Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Chang Yu11 Department of Biostatistics, Vanderbilt University, Nashville, TN, USA.
William C Nichols10 Division of Human Genetics, Cincinnati Children's Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Methodist Hospital · USUniversity of Cincinnati · USAllegheny General Hospital · USChildren's Medical Center · USColumbia University Irving Medical Center · USTufts University · USUniversity of Colorado Denver · USUniversity of Utah · USUniversity of Vermont · USVanderbilt University · USVanderbilt University Medical Center · US

Funding

National Biological Sample and Data Repository for PAHR24HL105333 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI NICHOLS, WILLIAM C · 2012 to 2016
$10.1M
NHLBI NIH HHS R24 HL105333
6 · The paper itself

Abstract

Diagnostic World Health Organization (WHO) Group 1 pulmonary arterial hypertension (PAH) and Diagnostic Group 1' pulmonary veno-occlusive disease (PVOD) and/or pulmonary capillary hemangiomatosis (PCH) are progressive and fatal disorders. Past registries provided important insights into these disorders, but did not include hormonal exposures or genomic data. The United States Pulmonary Hypertension Scientific Registry (USPHSR) will provide demographic, physiologic, anorexigen and hormone exposure, genomic, and survival data in the current therapeutic era for 499 patients diagnosed with PAH, PVOD, or PCH. The USPHSR also will explore the relationship between pharmacologic, non-pharmacologic, and dietary hormonal exposures and the increased risk for women to develop idiopathic or heritable PAH.

Indexed as

genotypehormonesPhenotypepulmonary hypertensiontoxins

Identifiers

PMID31099303
PMCPMC6540712
OpenAlexW2946091663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.