ArticleJournal of Korean medical science2019
Acute Necrotizing Encephalopathy in Children: a Long Way to Go.
Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Initiation of tocilizumab within 24 hours in acute necrotizing encephalopathy is related to a good outcome: a systematic review.Journal of neurology · 2025Pooled it
- Clinical and genetic characteristics of RANBP2 mutations in children with acute necrotizing encephalopathy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Influenza-associated neurological complications in pediatric patients: clinical characteristics, outcomes, and the neuroinfluenza severity score in the multicenter TURK-INF study.European journal of pediatrics · 2026Article
- Influenza Associated Encephalopathy, Encephalitis, and Acute Necrotizing Encephalitis in Adults: A Scoping Review of 83 Cases.Neurology international · 2026Review
- Article
- Effectiveness and safety of tocilizumab combined with different high-dose methylprednisolone regimens for acute necrotizing encephalopathy in children.Pediatric investigation · 2026Article
- Impact of demographic, clinical, and viral factors on severe influenza in young children in Fuzhou.Frontiers in public health · 2026Article
- Acute Necrotizing Encephalopathy in a Child With RANBP2 Mutation: A Case of Unanticipated Full Resolution.Cureus · 2025Article
- Bilateral Symmetrical Brain MRI Findings in Acute Necrotising Encephalopathy Type 1.Children (Basel, Switzerland) · 2025Article
- The Genetic Landscape of Acute Necrotizing Encephalopathy: Insights Into the Possible Pathogenesis.Journal of clinical neurology (Seoul, Korea) · 2025Article
- Acute necrotizing encephalopathy in an infant: A case report.Radiology case reports · 2025Article
- Acute necrotizing encephalopathy in adult patients with influenza: a case report and review of the literature.BMC infectious diseases · 2024Review
- Identification of neurological complications in childhood influenza: a random forest model.BMC pediatrics · 2024Article
- Peripheral macrophages drive CNS disease in the Ndufs4(-/-) model of Leigh syndrome.Brain pathology (Zurich, Switzerland) · 2023Article
- Acute necrotizing encephalopathy of childhood from Eastern Africa.Clinical case reports · 2023Article
- Risk factors for death associated with severe influenza in children and the impact of the COVID-19 pandemic on clinical characteristics.Frontiers in pediatrics · 2023Article
- Clinical characteristics and prognostic analysis of acute necrotizing encephalopathy of childhood: a retrospective study at a single center in China over 3 years.Frontiers in neurology · 2023Article
- Workshop on RanBP2/Nup358 and acute necrotizing encephalopathy.Nucleus (Austin, Tex.) · 2022Article
- The immune system as a driver of mitochondrial disease pathogenesis: a review of evidence.Orphanet journal of rare diseases · 2022Review
- Immune characteristics of children with autoimmune encephalitis and the correlation with a short-term prognosis.Italian journal of pediatrics · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute necrotizing encephalopathy (ANE) is a rare, but potentially life threatening neurological condition in children. This study aimed to investigate its clinical spectrum, diagnostic and therapeutic dilemma, and prognosis.
methodsTwelve children with ANE were included in the study. The diagnosis was made by clinical and radiological characteristics from January 1999 to December 2017 and their clinical data were retrospectively analyzed.
resultsA total of 12 children aged 6 to 93 months at onset (5 male: 7 female) were evaluated. The etiology was found in 4 of them (influenza A, H1N1; coxsackie A 16; herpes simplex virus; and
conclusionANE is a distinctive type of acute encephalopathy with diverse clinical spectrum. Even though the diagnostic criteria are available, they might not be watertight. In addition, treatment options are still limited. Further studies for better outcome are needed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.