Evidence map›Paper›PMID 31099190›Full record

ArticleBrain and behavior2019

AKT1, PRDM4, and BAX are the natural markers of psychological endurance threshold.

Zhijian Xu, Qicheng Jing, Houcan Zhang, Yue Liu

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Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Zhijian XuGuangdong Provincial Government Office, Guangzhou, China.
Qicheng JingInstitute of Psychology, Chinese Academy of Sciences, Peking, China.
Houcan ZhangDepartment of Psychology, Beijing Normal University, Peking, China.
Yue LiuDepartment of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.ORCID 0000-0001-8648-3856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAbnormal behavior can cause harm or loss to oneself, the family, and society and may be related to psychological endurance levels. With early identification and early intervention, the occurrence of harm can be prevented and the loss can be reduced. Now there is no clear definition of psychological endurance levels and no accurate measurement tools yet.

methodsThis study first proposes the concept of psychological endurance threshold (PET) and defines that as: "the psychological state threshold of human objective physiological characteristics and outbreaks of abnormal behavior led by subjective cognitive level difference". The study hypothesizes that human behavior is related to it, and constructs multiple measurement method tools to measure it.

resultsHere we show PET exists objectively and can be measured exactly by methods such as psychological endurance threshold measurement table, experience evaluation, dopamine level detection, and genetic testing. In particular, PET is determined by AKT1, PRDM4, and BAX which are the natural markers of PET.

conclusionsThe significance of this study is to discover people with abnormal expression of AKT1, PRDM4, and BAX who have lower PET and tend to commit abnormal behavior more easily. Understanding PET will enable people to make self-adjustment or to intervene by professionals as soon as possible and in a timely manner in the face of various negative stimuli in work and life, especially for people with lower PET, people should intervene as early as possible to reduce the harm to the individual, family and society.

Indexed as

Problem BehaviorAdultbcl-2-Associated X ProteinBehavioral SymptomsBiomarkersCorrelation of DataDNA-Binding ProteinsEmotional AdjustmentFemaleHumansMaleMiddle AgedProto-Oncogene Proteins c-aktTranscription FactorsAKT1 protein, humanbcl-2-Associated X ProteinBiomarkersDNA-Binding ProteinsPRDM4 protein, humanProto-Oncogene Proteins c-aktTranscription Factorsabnormal behaviorAKT1BAXPRDM4psychological endurance thresholdsocial harm

Identifiers

PMID31099190
PMCPMC6625479

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