Evidence map›Paper›PMID 31098958›Full record

ArticleJournal of the American Society for Mass Spectrometry2019

ETD-Cleavable Linker for Confident Cross-linked Peptide Identifications.

Bingqing Zhao, Colin P Reilly, James P Reilly

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Locating Polyubiquitin Receptors on the 19S Regulatory Proteasome ofJournal of the American Society for Mass Spectrometry · 2025
    Article
  2. Article
  3. Review
  4. Crosslinking mass spectrometry: A link between structural biology and systems biology.Protein science : a publication of the Protein Society · 2021
    Review
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bingqing ZhaoDepartment of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN, 47405, USA.
Colin P ReillyDepartment of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN, 47405, USA.
James P ReillyDepartment of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, IN, 47405, USA. reilly@indiana.edu.ORCID http://orcid.org/0000-0002-9784-1804
Indiana University Bloomington · US

Funding

Computational approaches to protein identification and quantification using MS/MSR01GM103725 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI RADIVOJAC, PREDRAG · 2012 to 2015
$1.7M
NIH HHS R01 GM103725NIH HHS U54 GM074807
6 · The paper itself

Abstract

Peptide cross-links formed using the homobifunctional-linker diethyl suberthioimidate (DEST) are shown to be ETD-cleavable. DEST has a spacer arm consisting of a 6-carbon alkyl chain and it cleaves at the amidino groups created upon reaction with primary amines. In ETD MS

Indexed as

Cross-Linking ReagentsCytochromes cElectron TransportMass SpectrometryPeptidesSignal-To-Noise RatioSpectrometry, Mass, Electrospray IonizationWorkflowCross-Linking ReagentsCytochromes cPeptidesCross-linkingElectron transfer dissociation

Identifiers

PMID31098958
OpenAlexW2944915128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.