ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2019
Turmeric Extract: Potential Use as a Prebiotic and Anti-Inflammatory Compound?
Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The efficacy and safety of Curcuma longa extract and curcumin supplements on osteoarthritis: a systematic review and meta-analysis.Bioscience reports · 2021Pooled it
- Trial
- Hypocholesterolemic agents and the gut microbiota: a review of interactions and modulatory activity.Pharmacological reports : PR · 2026Review
- Evaluation of antioxidant activities of bioactive peptides extracted from Curcuma longa and Curcuma caesia from South-eastern and North-Eastern India.Probiotics and antimicrobial proteins · 2026Article
- Fortification of non-dairy milk with date fruit, mustard seed, and turmeric: nutritional quality, probiotics viability, antimicrobial and antioxidant potentials.Scientific reports · 2025Article
- In Vitro Prebiotic Potential ofMolecules (Basel, Switzerland) · 2025Article
- Gandouling improves Wilson's disease liver fibrosis by modulating intestinal flora: a randomized, double-blind, placebo-controlled trial.Bioscience of microbiota, food and health · 2025Article
- Protective Effect of Curcumin on Metabolic Syndrome Components through the Microbiota.Current medicinal chemistry · 2025Review
- In-vitro screening of compatible synbiotics and (introducing) "prophybiotics" as a tool to improve gut health.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Physical, Chemical, and Sensory Properties of a Turmeric-Fortified Pineapple Juice Beverage.Foods (Basel, Switzerland) · 2023Article
- Recent Innovations in Non-dairy Prebiotics and Probiotics: Physiological Potential, Applications, and Characterization.Probiotics and antimicrobial proteins · 2023Review
- Testing the Feasibility and Dietary Impact of Macaroni Fortified with Green Tea and Turmeric Curcumin Extract in Diabetic Rats.Foods (Basel, Switzerland) · 2023Article
- Evaluation of dietary curcumin nanospheres as phytobiotics on growth performance, serum biochemistry, nutritional composition, meat quality, gastrointestinal health, and fecal condition of finishing pigs.Frontiers in veterinary science · 2023Article
- The influence of curcumin additives on the viability of probiotic bacteria, antibacterial activity against pathogenic microorganisms, and quality indicators of low-fat yogurt.Frontiers in nutrition · 2023Article
- Natural Topical Treatment Contributes to a Reduction of Dry Scalp Symptoms in Children.Clinical, cosmetic and investigational dermatology · 2023Article
- Pharmacological considerations for treating neuroinflammation with curcumin in Alzheimer's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- Curcumin Supplementation Ameliorates Bile Cholesterol Supersaturation in Hamsters by Modulating Gut Microbiota and Cholesterol Absorption.Nutrients · 2022Article
- The Gene Regulatory Roles of Herbal Extracts on the Growth, Immune System, and Reproduction of Fish.Animals : an open access journal from MDPI · 2021Review
- Potential Inhibitors for SARS-CoV-2 and Functional Food Components as Nutritional Supplement for COVID-19: A Review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2020Review
- Microbial-Based and Microbial-Targeted Therapies for Inflammatory Bowel Diseases.Digestive diseases and sciences · 2020Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Prebiotics are regarded as the non-digestible food constituents that are selectively consumed by health-promoting bacteria (probiotics). In fact, a number of active metabolites is released due to intensive interaction between prebiotics and probiotics in the gut which exert local and systemic beneficial effects including regulation of intestinal disorders and modulation of host immunity. Turmeric is one of the most important medicinal herbaceous that is derived from Curcuma longa rhizome. Curcumin is a well-recognized component of turmeric which contributes to the prevention of multiple inflammatory diseases. Despite curcumin as a well-known compound, few researches have focused on the turmeric extract (TE) and its potential as prebiotic and anti-inflammatory compound. The aim of this study was to evaluate the prebiotic potential and some functional-structural properties of TE. The Fourier-transform-infrared spectroscopy (FTIR) spectrum of TE showed identical peaks that belonged to β configuration in pyranose and glycosidic bonds. High performance liquid chromatography (HPLC) analysis revealed the presence of potent phenolic and flavonoid anti-oxidants and curcuminoids, and some functional monosaccharides. TE demonstrated excellent resistance to artificial human gastric and intestine juice compared to the standard prebiotic (inulin) (p ≤ 0.05). Interestingly, our time course experiment showed that TE not only is digested by probiotics including Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis BB12, but also supports the growth of these bacteria even after 72 h (p ≤ 0.05). To our knowledge, this is the first report evaluating prebiotic potential of TE and exploring its suppressive effects on LPS induced IL-8 production in HT29-19A cell line.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.