Evidence map›Paper›PMID 31098856›Full record

ArticleCancer causes & control : CCC2019

Cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program.

Sun Hee Rim, Benjamin T Allaire, Donatus U Ekwueme, Jacqueline W Miller, Sujha Subramanian, Ingrid J Hall, Thomas J Hoerger

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Systematic Review of the Cost Effectiveness of Breast Cancer Prevention, Screening, and Treatment Interventions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
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  16. Cost-Effectiveness of Breast Cancer Screening in Shiraz, Iran.International journal of preventive medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sun Hee RimDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS S107-4, Atlanta, GA, 30341, USA. srim@cdc.gov.ORCID http://orcid.org/0000-0002-1806-1683
Benjamin T AllaireRTI International, Research Triangle Park, NC, USA.
Donatus U EkwuemeDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS S107-4, Atlanta, GA, 30341, USA.
Jacqueline W MillerDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS S107-4, Atlanta, GA, 30341, USA.
Sujha SubramanianRTI International, Research Triangle Park, NC, USA.
Ingrid J HallDivision of Cancer Prevention and Control, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MS S107-4, Atlanta, GA, 30341, USA.
Thomas J HoergerRTI International, Research Triangle Park, NC, USA.

Funding

CDC HHS This research was supported by Contract No. 200-2008-27958 from the Centers for Disease Control and PreventionIntramural CDC HHS CC999999
6 · The paper itself

Abstract

purposeTo estimate the cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP).

methodsUsing a modified CISNET breast cancer simulation model, we estimated outcomes for women aged 40-64 years associated with three scenarios: breast cancer screening within the NBCCEDP, screening in the absence of the NBCCEDP (no program), and no screening through any program. We report screening outcomes, cost, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratios (ICERs), and sensitivity analyses results.

resultsCompared with no program and no screening, the NBCCEDP lowers breast cancer mortality and improves QALYs, but raises health care costs. Base-case ICER for the program was $51,754/QALY versus no program and $50,223/QALY versus no screening. Probabilistic sensitivity analysis ICER for the program was $56,615/QALY [95% CI $24,069, $134,230/QALY] versus no program and $51,096/QALY gained [95% CI $26,423, $97,315/QALY] versus no screening.

conclusionsOn average, breast cancer screening in the NBCCEDP was cost-effective compared with no program or no screening.

Indexed as

AdultBreast NeoplasmsCost-Benefit AnalysisEarly Detection of CancerFemaleHumansMass ScreeningMiddle AgedNational Health ProgramsQuality-Adjusted Life YearsBreast cancerCost-effectivenessEconomic analysisNBCCEDPScreening

Identifiers

PMID31098856
PMCPMC6613985

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.