ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Using path analysis to investigate the relationships between depression, anxiety, and health-related quality of life among patients with coronary artery disease.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Pooled it
- Higher anxiety score in patients with non-obstructive coronary artery disease.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026Article
- Anxiety and Depression Status of Patients With Coronary Atherosclerotic Heart Disease and Its Influencing Factors.Actas espanolas de psiquiatria · 2025Article
- Enhanced External Counterpulsation Outcomes Study: Retrospective Analyses of Data Obtained from Patients at a Single Medical Center in United States.The International journal of angiology : official publication of the International College of Angiology, Inc · 2024Article
- Quality of Life and Mental Health of Chinese Sexual and Gender Minority Women and Cisgender Heterosexual Women: Cross-sectional Survey and Mediation Analysis.JMIR public health and surveillance · 2023Article
- Sexual Satisfaction and Quality of Life in Cardiovascular Patients: The Mediating Role of Anxiety.Healthcare (Basel, Switzerland) · 2023Article
- The relationship between liver function and neurophysiological factors in depressed individuals: a cross-sectional study using an integrated "East meets West" medicine approach.Frontiers in psychiatry · 2023Article
- Health-related quality of life and its related factors in coronary heart disease patients: results from the Henan Rural Cohort study.Scientific reports · 2021Article
- Psychosocial Risk Factors in Cardiac Rehabilitation: Time to Screen Beyond Anxiety and Depression.Global heart · 2021Article
- The relationship between coronary artery disease and depression and anxiety scores.Northern clinics of Istanbul · 2020Review
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purposeDemographic and clinical indicators usually influence depression, anxiety, and health-related quality of life (HRQoL) in patients with coronary artery disease (CAD). The aim of this study was to assess the direct and indirect association that existed among the identified variables, psychosocial status, and HRQoL in CAD patients.
methodsCAD patients with at least one of the main coronary artery and/or branch stenosis over 50% were eligible for inclusion. HRQoL, depression, and anxiety were tested by questionnaires within 3 days after angiography. Mono-factor and multiple linear regression models were used to examine the independent associations of depression, anxiety, and HRQoL. A path analysis was conducted to examine the association among demographic/clinical indicators, depression, anxiety, and HRQoL.
resultsThe sample consisted of 414 subject, patients with depression accounted for 40.82%, and patients with anxiety accounted for 25.12%. The direct effects of SAS scores on HRQoL (B = - 0.26, β = - 0.16), of SDS scores on HRQoL (B = - 0.70, β = - 0.47), of gender on HRQoL (B = 4.05, β = 0.17), and of NYHA classification on HRQoL (B = - 3.46, β = - 0.18) were significant (p < 0.001). The indirect effects of gender on HRQoL (B = 2.16, β = 0.09) and of Gensini scores on HRQoL (B = - 0.06, β = - 0.08) were also statistically significant (p < 0.001).
conclusionsDepression and anxiety were common CAD patients and played an important role in HRQoL. Gender differences were found in determinants of HRQoL and the state of depression and anxiety directly, and women's anxiety, depression, and quality of life were worse than men's. NYHA classification and Gensini scores also played direct and indirect role in HRQoL, respectively.
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