Evidence map›Paper›PMID 31098719›Full record

ArticleMikrochimica acta2019

Electrochemical immunoassay for the tumor marker CD25 by coupling magnetic sphere-based enrichment and DNA based signal amplification.

Shuang Cao, Qiuguo Wang, Xiangyue Xiao, Ting Li, Minghui Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shuang CaoDepartment of General Surgery, The Second Xiang-ya Hospital, Central South University, Changsha, 410011, China.
Qiuguo WangDepartment of General Surgery, The Second Xiang-ya Hospital, Central South University, Changsha, 410011, China.
Xiangyue XiaoDepartment of General Surgery, The Second Xiang-ya Hospital, Central South University, Changsha, 410011, China.
Ting LiDepartment of General Surgery, The Second Xiang-ya Hospital, Central South University, Changsha, 410011, China. liting001@csu.edu.cn.
Minghui YangKey Laboratory of Hunan Province for Water Environment and Agriculture Product Safety, College of Chemistry and Chemical Engineering, Central South University, Changsha, 410083, China. yangminghui@csu.edu.cn.ORCID 0000-0002-7612-8137
Central South University · CN

Funding

National Natural Science Foundation of China 21575165
6 · The paper itself

Abstract

Interleukin-2 receptor alpha chain (also called CD25) is a tumor biomarker that is frequently expressed on the surface of hematological tumor cells. The authors describe an electrochemical immunoassay for CD25 that involves (a) enrichment of CD25 from samples by using magnetic nanospheres, and (b) utilization of DNA modulated current as the detection signal. Primary anti-CD25 antibody was immobilized onto F

Indexed as

Biosensing TechniquesElectrochemical TechniquesImmunoassayNucleic Acid Amplification TechniquesBiomarkers, TumorDNA, NeoplasmFerrosoferric OxideHumansInterleukin-2 Receptor alpha SubunitMagnetic PhenomenaMagnetite NanoparticlesBiomarkers, TumorDNA, NeoplasmFerrosoferric OxideIL2RA protein, humanInterleukin-2 Receptor alpha SubunitMagnetite NanoparticlesCD25ImmunoassayMagnetic spheresMolybdatePolycytosine DNA

Identifiers

PMID31098719
OpenAlexW2945048008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.