Evidence map›Paper›PMID 31098674›Full record

ArticleMikrochimica acta2019

Gold nanoclusters as a near-infrared fluorometric nanothermometer for living cells.

Hailiang Zhang, Wenxiu Han, Xiaozheng Cao, Tang Gao, Ranran Jia, Meihui Liu, Wenbin Zeng

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Photoluminescent nanocluster-based probes for bioimaging applications.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2022
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hailiang ZhangXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Wenxiu HanInstitute of Clinical Pharmacy & Pharmacology, Jining First People's Hospital, Jining Medical University, Jining, 272000, China.
Xiaozheng CaoXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Tang GaoXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Ranran JiaXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Meihui LiuXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China.
Wenbin ZengXiangya School of Pharmaceutical Sciences, Central South University, Changsha, 410013, China. wbzeng@hotmail.com.

Funding

Key Research Project of Science and Technology Foundation of Hunan Province 2017SK2093Key Research Project of Science and Technology Foundation of Hunan Province 2018GK5004National Natural Science Foundation of China 81671756Projects of Medical and Health Technology Development Program in Shandong Province 2018WS471The State Key Laboratory of Drug Research SIMM1803KF-14
6 · The paper itself

Abstract

The authors describe the syntheses and application of glutathione-capped gold nanoclusters (AuNCs) with thermoresponsive properties. The AuNCs have excitation/emission maxima at 430/610 nm and the bright redfluorescence changes along with the temperature in the range from 0 to 90 °C which covers the normal temperature range of living cells. In the range of physiological temperatures (35-42 °C), the temperature resolution is 0.73 °C. The AuNCs display excellent colloidal stability and biocompatibility. They were used for fluorometric temperature detection and imaging of hepatic stellate cells. With such attractive features, the AuNCs are quite promising luminescence nanothermometers. Graphical abstract Schematic presentation of the fluorescence of glutathione-capped gold nanoclusters (AuNCs) as nanothermometers in living cells. The AuNCs have excitation/emission maxima at 430/610 nm and the red fluorescence changes with temperature in a wide range of 0 to 90 °C which covers the normal temperature of living cells.

Indexed as

FluorometryNanotechnologyOptical ImagingTemperatureCells, CulturedCell SurvivalGoldHumansInfrared RaysMetal NanoparticlesGoldAuNCsCellular imagingNanothermometerNIR fluorescenceTemperature detection

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.