ArticleEuropean heart journal2019
Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry.
Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph
Article in European heart journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05731830 (Takotsubo Syndrome and Air Pollution), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
10.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Takotsubo Syndrome and Air Pollution: the "Tako-Air" Study
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Predictors of high-grade atrioventricular block recovery in Takotsubo cardiomyopathy: a systematic review of case reports.Open heart · 2026Pooled it
- Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Clinical characteristics and outcomes of patients with takotsubo syndrome versus spontaneous coronary artery dissection.Cardiology journal · 2023Trial
- Article
- Takotsubo syndrome presenting as ventricular fibrillation cardiopulmonary arrest coupled with complete heart block.Journal of cardiology cases · 2026Article
- Early Ventricular Arrhythmias Correlate with Adverse Outcome in Takotsubo Syndrome: Analysis of a Large Single-Center Database.Journal of cardiovascular development and disease · 2025Article
- Takotsubo Syndrome, Complete Heart Block, and Cardiac Arrest: A Clinical Challenge.Arquivos brasileiros de cardiologia · 2025Article
- Takotsubo syndrome: Unraveling the mystery behind its triggers (Review).International journal of molecular medicine · 2025Review
- Exploring sex-specific clinical features in Chinese patients with Takotsubo syndrome.BMC cardiovascular disorders · 2025Article
- Takotsubo Syndrome Development Immediately Following Hemodialysis Initiation.Internal medicine (Tokyo, Japan) · 2025Article
- Takotsubo Syndrome: An International Expert Consensus Report on Practical Challenges and Specific Conditions (Part-1: Diagnostic and Therapeutic Challenges)Balkan medical journal · 2024Article
- Repolarization Injury and Occurrence of Torsades de Pointes During Acute Takotsubo Syndrome.JACC. Advances · 2024Article
- Clinical Applications of Cardiac Magnetic Resonance Parametric Mapping.Diagnostics (Basel, Switzerland) · 2024Review
- Aberrant brain-heart coupling is associated with the severity of post cardiac arrest brain injury.Annals of clinical and translational neurology · 2024Article
- Prognostic Utility of Society for Cardiovascular Angiography and Interventions Shock Stage Approach for Classifying Cardiogenic Shock Severity in Takotsubo Syndrome.Journal of the American Heart Association · 2024Article
- Takotsubo Syndrome and Coronary Artery Disease: Which Came First-The Chicken or the Egg?Journal of cardiovascular development and disease · 2024Review
- C-Reactive Protein: Pathophysiology, Diagnosis, False Test Results and a Novel Diagnostic Algorithm for Clinicians.Diseases (Basel, Switzerland) · 2023Review
- Calcineurin signaling promotes takotsubo syndrome.Nature cardiovascular research · 2023Article
- Article
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Authors and funding
84 authors at 20 institutions in 13 countries.
Sebastiano GiliDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Victoria L CammannDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Susanne A SchlossbauerDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Ken KatoDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Fabrizio D'AscenzoDivision of Cardiology, Department of Medical Sciences, AOU Citta della Salute e della Scienza, University of Turin, Turin, Italy.
Davide Di VeceDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Stjepan JurisicDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Jozef MicekDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Slayman ObeidDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Beatrice BacchiDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Konrad A SzawanDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Flurina FamosDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Annahita SarconKeck School of Medicine, University of Southern California, Los Angeles CA, USA.
Rena LevinsonDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Katharina J DingDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Burkhardt SeifertDivision of Biostatistics, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Olivia LenoirDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Eduardo BossoneDivision of Cardiology 'Antonio Cardarelli' Hospital, Naples, Italy.
Rodolfo CitroHeart Department, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Salerno, Italy.
Jennifer FrankeDepartment of Cardiology, Heidelberg University Hospital, Heidelberg, Germany.
L Christian NappDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Milosz JaguszewskiFirst Department of Cardiology, Medical University of Gdansk, Gdansk, Poland.
Michel NoutsiasDivision of Cardiology, Department of Internal Medicine III, Angiology and Intensive Medical Care, University Hospital Halle, Martin-Luther-University Halle, Halle (Saale), Germany.
Thomas MünzelCenter for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany.
Maike KnorrCenter for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany.
Susanne HeinerCenter for Cardiology, Cardiology 1, University Medical Center Mainz, Mainz, Germany.
Hugo A KatusDepartment of Cardiology, Heidelberg University Hospital, Heidelberg, Germany.
Christof BurgdorfHeart and Vascular Centre Bad Bevensen, Bad Bevensen, Germany.
Heribert SchunkertDeutsches Herzzentrum München, Technische Universität München, Munich, Germany.
Holger ThieleDepartment of Internal Medicine/Cardiology, University of Leipzig-Heart Center, Leipzig, Germany.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Carsten TschöpeDepartment of Cardiology, Charité, Campus Rudolf Virchow, Berlin, Germany.
Burkert M PieskeDepartment of Cardiology, Charité, Campus Rudolf Virchow, Berlin, Germany.
Lawrence RajanTJ Health Partners Heart and Vascular, Glasgow, KY, USA.
Guido MichelsDepartment of Internal Medicine III, Heart Center University of Cologne, Cologne, Germany.
Roman PfisterDepartment of Internal Medicine III, Heart Center University of Cologne, Cologne, Germany.
Alessandro CuneoKrankenhaus 'Maria Hilf' Medizinische Klinik, Stadtlohn, Germany.
Claudius JacobshagenClinic for Cardiology and Pneumology, Georg August University Goettingen, Goettingen, Germany.
Gerd HasenfußDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.
Mahir KarakasDepartment of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany.
Wolfgang KoenigDeutsches Herzzentrum München, Technische Universität München, Munich, Germany.
Wolfgang RottbauerDepartment of Internal Medicine II-Cardiology, University of Ulm, Medical Center, Ulm, Germany.
Samir M SaidInternal Medicine/Cardiology, Angiology, and Pneumology, Magdeburg University, Magdeburg, Germany.
Ruediger C Braun-DullaeusInternal Medicine/Cardiology, Angiology, and Pneumology, Magdeburg University, Magdeburg, Germany.
Adrian BanningDepartment of Cardiology, John Radcliffe Hospital, Oxford University Hospitals, Oxford, UK.
Florim CuculiDepartment of Cardiology, Kantonsspital Lucerne, Lucerne, Switzerland.
Richard KobzaDepartment of Cardiology, Kantonsspital Lucerne, Lucerne, Switzerland.
Thomas A FischerDepartment of Cardiology, Kantonsspital Winterthur, Winterthur, Switzerland.
Tuija VasankariHeart Center, Turku University Hospital and University of Turku, Turku, Finland.
K E Juhani AiraksinenHeart Center, Turku University Hospital and University of Turku, Turku, Finland.
Grzegorz OpolskiDepartment of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Rafal DworakowskiDepartment of Cardiology, Kings College Hospital, Kings Health Partners, London, UK.
Philip MacCarthyDepartment of Cardiology, Kings College Hospital, Kings Health Partners, London, UK.
Christoph KaiserDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Stefan OsswaldDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.
Leonarda GaliutoDepartment of Cardiovascular Sciences, Catholic University of the Sacred Heart Rome, Rome, Italy.
Filippo CreaDepartment of Cardiovascular Sciences, Catholic University of the Sacred Heart Rome, Rome, Italy.
Wolfgang DichtlUniversity Hospital for Internal Medicine III (Cardiology and Angiology), Medical University Innsbruck, Innsbruck, Austria.
Klaus EmpenDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Stephan B FelixDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.
Clément DelmasDepartment of Cardiology and Cardiac Imaging Center, University Hospital of Rangueil, Toulouse, France.
Olivier LairezDepartment of Cardiology and Cardiac Imaging Center, University Hospital of Rangueil, Toulouse, France.
Ibrahim El-BattrawyFirst Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM) University of Heidelberg, Mannheim, Germany.
Ibrahim AkinFirst Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM) University of Heidelberg, Mannheim, Germany.
Martin BorggrefeFirst Department of Medicine, Faculty of Medicine, University Medical Centre Mannheim (UMM) University of Heidelberg, Mannheim, Germany.
Ekaterina GilyarovaIntensive coronary care Unit, Moscow City Hospital # 1 named after N. Pirogov, Moscow, Russia.
Alexandra ShilovaIntensive coronary care Unit, Moscow City Hospital # 1 named after N. Pirogov, Moscow, Russia.
Mikhail GilyarovIntensive coronary care Unit, Moscow City Hospital # 1 named after N. Pirogov, Moscow, Russia.
John D HorowitzDiscipline of Medicine, Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia.
Martin KozelThird Medical Faculty, Charles University in Prague and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Petr TousekThird Medical Faculty, Charles University in Prague and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Petr WidimskýThird Medical Faculty, Charles University in Prague and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
David E WinchesterDepartment of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
Christian UkenaKlinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Fiorenzo GaitaDivision of Cardiology, Department of Medical Sciences, AOU Citta della Salute e della Scienza, University of Turin, Turin, Italy.
Carlo Di MarioStructural Interventional Cardiology, University Hospital Careggi, Florence, Italy.
Manfred B WischnewskyFB Mathematics and Computer Science, University of Bremen, Bremen, Germany.
Jeroen J BaxDepartment of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands.
Abhiram PrasadDepartment of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
Michael BöhmKlinik für Innere Medizin III, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Frank RuschitzkaDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Thomas F LüscherCenter for Molecular Cardiology, Schlieren Campus, University of Zurich, Zurich, Switzerland.
Jelena R GhadriDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
Christian TemplinDepartment of Cardiology, University Heart Center, University Hospital Zurich, Switzerland.
University Hospital of Zurich · CHHeidelberg University · DECity Clinical Hospital · RUCharité - Universitätsmedizin Berlin · DEDeutsches Herzzentrum München · DEHôpital Rangueil · FRKing's College Hospital · GBLuzerner Kantonsspital · CHMedizinische Hochschule Hannover · DEUniversità Cattolica del Sacro Cuore · ITUniversitätsklinikum des Saarlandes · DEUniversity Hospital Kralovske Vinohrady · CZUniversity Hospital Magdeburg · DEUniversity Hospital of Basel · CHUniversity Medical Center of the Johannes Gutenberg University Mainz · DEUniversity of Cologne · DEUniversity of Turin · ITAzienda Ospedaliero-Universitaria Careggi · ITCharles University · CZGdańsk Medical University · PL
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsWe aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). METHODS AND
resultsWe reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were included. Compared with patients without CA, CA patients were more likely to be younger, male, and have apical TTS, atrial fibrillation (AF), neurologic comorbidities, physical triggers, and longer corrected QT-interval and lower left ventricular ejection fraction on admission. In all, 57.1% of patients with CA at admission had ventricular fibrillation/tachycardia, while 73.7% of patients with CA in the acute phase had asystole/pulseless electrical activity. Patients with CA showed higher 60-day (40.3% vs. 4.0%, P < 0.001) and 5-year mortality (68.9% vs. 16.7%, P < 0.001) than patients without CA. T-wave inversion and intracranial haemorrhage were independently associated with higher 60-day mortality after CA, whereas female gender was associated with lower 60-day mortality. In the acute phase, CA occurred less frequently in females and more frequently in patients with AF, ST-segment elevation, and higher C-reactive protein on admission.
conclusionsCardiac arrest is relatively frequent in TTS and is associated with higher short- and long-term mortality. Clinical and electrocardiographic parameters independently predicted mortality after CA.
Indexed as
FemaleHeart ArrestHumansMaleMiddle AgedPrognosisRegistriesRetrospective StudiesSurvival AnalysisTakotsubo CardiomyopathyAcute heart failureBroken heart syndromeCardiac arrestOutcomeTakotsubo syndrome
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LicenceCC BY-NC
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Registered trials
NCT05731830ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.