ArticleCommunications biology2019
Transcriptome analysis of activated sludge microbiomes reveals an unexpected role of minority nitrifiers in carbon metabolism.
Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Recent Advanced Technologies for the Characterization of Xenobiotic-Degrading Microorganisms and Microbial Communities.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Microbial diversity supports nitrification: insights from a full-scale anoxic/oxic wastewater treatment process.Applied and environmental microbiology · 2025Article
- Replacing methanol with internally produced VFA-based carbon source for denitrification at the Henriksdal WWTP.Water science and technology : a journal of the International Association on Water Pollution Research · 2025Article
- Optimization of Mapping Tools and Investigation of Ribosomal RNA Influence for Data-Driven Gene Expression Analysis in Complex Microbiomes.Microorganisms · 2025Article
- Metatranscriptomes of activated sludge microbiomes from saline wastewater treatment plant.Scientific data · 2025Article
- Phyllosphere of senescent crops as a microbial NFrontiers in microbiology · 2025Article
- Total RNA analysis of the active microbiome on moving bed biofilm reactor carriers under incrementally increasing micropollutant concentrations.FEMS microbiology ecology · 2024Article
- Long-duration environmental biosensing by recording analyte detection in DNA using recombinase memory.Applied and environmental microbiology · 2024Article
- Alternative stable states, nonlinear behavior, and predictability of microbiome dynamics.Microbiome · 2023Article
- Existence and distribution of novel phylotypes ofiScience · 2022Article
- Bacterial growth in multicellular aggregates leads to the emergence of complex life cycles.Current biology : CB · 2022Article
- Microbe-assisted phytoremediation of environmental pollutants and energy recycling in sustainable agriculture.Archives of microbiology · 2021Review
- Insecticide resistance by a host-symbiont reciprocal detoxification.Nature communications · 2021Article
- All creatures great and small: celebrating the microbiome.Communications biology · 2021Article
- Visualization of Gene Reciprocity among Lactic Acid Bacteria in Yogurt by RNase H-Assisted Rolling Circle Amplification-FluorescenceMicroorganisms · 2021Article
- Transition of microbial community structures after development of membrane fouling in membrane bioreactors (MBRs).AMB Express · 2020Article
- New Frontiers of Anaerobic Hydrocarbon Biodegradation in the Multi-Omics Era.Frontiers in microbiology · 2020Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although metagenomics researches have illuminated microbial diversity in numerous biospheres, understanding individual microbial functions is yet difficult due to the complexity of ecosystems. To address this issue, we applied a metagenome-independent, de novo assembly-based metatranscriptomics to a complex microbiome, activated sludge, which has been used for wastewater treatment for over a century. Even though two bioreactors were operated under the same conditions, their performances differed from each other with unknown causes. Metatranscriptome profiles in high- and low-performance reactors demonstrated that denitrifiers contributed to the anaerobic degradation of heavy oil; however, no marked difference in the gene expression was found. Instead, gene expression-based nitrification activities that fueled the denitrifiers by providing the respiratory substrate were notably high in the high-performance reactor only. Nitrifiers-small minorities with relative abundances of <0.25%-governed the heavy-oil degradation performances of the reactors, unveiling an unexpected linkage of carbon- and nitrogen-metabolisms of the complex microbiome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.