Evidence map›Paper›PMID 31098304›Full record

ArticleSignal transduction and targeted therapy

Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 in

Yiping Chen, Yang Zhang, Hui Ye, Yanshu Dou, Deren Lu, Xiaolu Li, Andrew H Limper, Junhong Han, Dan Su

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Signal transduction and targeted therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yiping Chen *1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Yang Zhang *1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Hui Ye2Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu, Sichuan P. R. China.
Yanshu Dou1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Deren Lu1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Xiaolu Li3International Center for Translational Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, P.R. China, Chengdu, Sichuan P. R. China.
Andrew H Limper4Thoracic Diseases Research Unit, Mayo Clinic College of Medicine, Rochester, MN USA.
Junhong Han1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Dan Su1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan P. R. China.
Sichuan University · CNState Key Laboratory of BiotherapyMayo Clinic · USSichuan Academy of Traditional Chinese Medicine · CNWest China Hospital of Sichuan University · CN

Funding

Pneumocystis: Macrophage & Epithelial ActivationR01HL062150 · NHLBI · MAYO CLINIC ROCHESTER · PI ANDREW H LIMPER · 1998 to 2026
$9.2M
NHLBI NIH HHS R01 HL062150
6 · The paper itself

Abstract

Rtt109 is a histone acetyltransferase (HAT) that is a potential therapeutic target in conditioned pathogenic fungi

Indexed as

Infectious diseasesStructural biology

Identifiers

PMID31098304
PMCPMC6509256
OpenAlexW2944623802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.