Evidence map›Paper›PMID 31097917›Full record

ArticleSaber (Cumana, Venezuela)

COMPARATIVE ANALYSIS OF BIOLOGICAL AND BIOCHEMICAL VENOM CHARACTERISTICS OF NORTH AND SOUTH AMERICAN

Elda E Sánchez, Alexis Rodríguez-Acosta

Abstract read
In one paragraph

Article in Saber (Cumana, Venezuela). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elda E SánchezTexas A&M University-Kingsville, National Natural Toxins Research Center, Kingsville, USA.
Alexis Rodríguez-AcostaUniversidad Central de Venezuela, Instituto Anatómico, Laboratorio de Inmunoquímica y Ultraestructura, Caracas, Venezuela rodriguezacosta1946@yahoo.es.
Central University of Venezuela · VE

Funding

Viper Resource Grant at Texas A&M University-KingsvilleP40OD010960 · OD · TEXAS A&M UNIVERSITY-KINGSVILLE · PI Elda E. Sanchez · 2012 to 2026
$9.2M
NIH HHS P40 OD010960
6 · The paper itself

Abstract

In this study, venom samples of rattlesnakes from the United States of America and Venezuela Bolivarian Republic were tested for their gelatinase, fibrinolytic, hemorrhagic and coagulant activities, as well as inhibition of platelet function. Electrophoretic titration curves on polyacrylamide gel were used to compare protein composition. There were different protease activities in the venoms. Hemorrhagic activity showed high geographic variation, but northern specimens had a higher trend in this parameter. Differences in venom protein conformation were palpable between snakes from the North and South America. There was a distinct protein composition among all venoms, several venoms presented hemorrhagic and fibrinolytic activities, and different performance on platelet assays. These results demonstrate the interesting differences between North and South America

Indexed as

agregación plaquetariaCoagulaciónCoagulationfibrinólisisfibrinolysishemorragiahemorrhagicplatelet functionsnake venomveneno de serpiente

Identifiers

PMID31097917
PMCPMC6516075
OpenAlexW2462873656

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.