Evidence map›Paper›PMID 31097877›Full record

ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2019

Use of a colorimetric assay to evaluate the proliferation of canine mammary tumor cells exposed to propofol.

Martina Argano, Raffaella De Maria, Katrin Rodlsberger, Paolo Buracco, M Paula Larenza Menzies

Erratum issuedAbstract read
PubMed Full text at PMC
In one paragraph

Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Martina ArganoAnaesthesiology and Perioperative Intensive-Care Medicine, Veterinary University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria (Argano, Rodlsberger, Menzies); Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland (Argano); Department of Veterinary Sciences-Surgery Unit, Veterinary Faculty of the University of Turin, Italy (De Maria, Buracco).
Raffaella De MariaAnaesthesiology and Perioperative Intensive-Care Medicine, Veterinary University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria (Argano, Rodlsberger, Menzies); Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland (Argano); Department of Veterinary Sciences-Surgery Unit, Veterinary Faculty of the University of Turin, Italy (De Maria, Buracco).
Katrin RodlsbergerAnaesthesiology and Perioperative Intensive-Care Medicine, Veterinary University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria (Argano, Rodlsberger, Menzies); Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland (Argano); Department of Veterinary Sciences-Surgery Unit, Veterinary Faculty of the University of Turin, Italy (De Maria, Buracco).
Paolo BuraccoAnaesthesiology and Perioperative Intensive-Care Medicine, Veterinary University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria (Argano, Rodlsberger, Menzies); Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland (Argano); Department of Veterinary Sciences-Surgery Unit, Veterinary Faculty of the University of Turin, Italy (De Maria, Buracco).
M Paula Larenza MenziesAnaesthesiology and Perioperative Intensive-Care Medicine, Veterinary University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria (Argano, Rodlsberger, Menzies); Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland (Argano); Department of Veterinary Sciences-Surgery Unit, Veterinary Faculty of the University of Turin, Italy (De Maria, Buracco).
University of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drugs applied on human cancer cells can influence the rate of cell proliferation. The present study investigates the use of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrasodium bromide (MTT) colorimetric assay to evaluate canine tumor cell proliferation after exposure to the injectable anesthetic, propofol. Primary (CIPp) and metastatic (CIPm) canine tubular adenocarcinoma cell lines were incubated with cell culture medium (control) or propofol (1, 5, and 10 μg/mL). The MTT assays were performed after 6 and 12 hours of exposure. Measurements of absorbance were obtained for each condition with a spectrophotometer and compared with controls using a 3-way analysis of variance (

Indexed as

Mammary Neoplasms, AnimalAdenocarcinomaAnimalsCell Line, TumorCell ProliferationColorimetryColoring AgentsDog DiseasesDogsFemaleHypnotics and SedativesPropofolTetrazolium SaltsThiazolesColoring AgentsHypnotics and SedativesPropofolTetrazolium SaltsThiazolesthiazolyl blue

Identifiers

PMID31097877
PMCPMC6450161
OpenAlexW2972991360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.