ArticleScientific reports2019
Deformities of the Globus Pallidus are Associated with Severity of Suicidal Ideation and Impulsivity in Patients with Major Depressive Disorder.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- A case of depression with psychotic features associated with hemoglobin Manukau mutation.PCN reports : psychiatry and clinical neurosciences · 2025Article
- Psychoneuroimmunoendocrinological and neuroanatomical basis of suicidal behavior: potential therapeutic strategies with a focus on transcranial magnetic stimulation (TMS).Brain, behavior, & immunity - health · 2025Article
- Effects of depression and anxiety symptoms on cognitive inhibition: A cross-sectional study of structural and functional MRI evidence.Medicine · 2025Observational
- A Naturalistic Prospective Study of the Prognostic Impact of EPHX2 in Major Depressive Disorder: Impulsivity may be an Important Factor.Depression and anxiety · 2025Observational
- Topological differences of striato-thalamo-cortical circuit in functional brain network between premature ejaculation patients with and without depression.Brain and behavior · 2024Article
- Clinical and Neuropsychological Features of Suicide Attempters in Tehran, Iran: A Comparative Study.Medical journal of the Islamic Republic of Iran · 2024Article
- Serial mediation of the relationship between impulsivity and suicidal ideation by depression and hopelessness in depressed patients.BMC public health · 2023Article
- Sex Differences of the Functional Brain Activity in Treatment-Resistant Depression: A Resting-State Functional Magnetic Resonance Study.Brain sciences · 2022Article
- Trait Anxiety Mediates Impulsivity and Suicidal Ideation in Depression During COVID-19 Pandemic.Frontiers in psychiatry · 2022Article
- Resting-State Functional Magnetic Resonance Image to Analyze Electrical Biological Characteristics of Major Depressive Disorder Patients with Suicide Ideation.Computational and mathematical methods in medicine · 2022Article
- Brain Correlates of Suicide Attempt in 18,925 Participants Across 18 International Cohorts.Biological psychiatry · 2021Article
- Inter-hemispheric Functional Connections Are More Vulnerable to Attack Than Structural Connection in Patients With Irritable Bowel Syndrome.Journal of neurogastroenterology and motility · 2021Article
- Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder.Frontiers in psychiatry · 2021Review
- Hippocampal Subfield Volumes in Major Depressive Disorder Adolescents with a History of Suicide Attempt.BioMed research international · 2021Article
- Local shape volume alterations in subcortical structures of suicide attempters with major depressive disorder.Human brain mapping · 2020Article
- The Relationship between Performance of Attention Task and Suicidal Ideation in Korean Patients with Mood Disorders.Psychiatry investigation · 2020Article
- Identifying common and distinct subcortical volumetric abnormalities in 3 major psychiatric disorders: a single-site analysis of 640 participants.Journal of psychiatry & neuroscience : JPNArticle
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroimaging research increasingly suggests there are biological features related to suicidal risk, including brain morphometric features, leading to an elaborate suicide risk assessment. However, few studies have focused on the severity of suicidal ideation and its association with subcortical anatomy in patients with major depressive disorder (MDD). Here, we mainly investigated whether specific structural differences were present in MDD patients with and without suicidal ideation; and supplemented comparison with and without suicidal attempt. We hypothesized that structures associated with suicidal ideation would be derived from a combination of depression and impulsivity. Local atrophy of subcortical structures in 48 patients with MDD (24 with suicidal ideation and 24 without) and 25 age- and sex-matched healthy controls were compared using a surface-based shape analysis method. There was no difference in brain volume between MDD patients with or without suicidal ideations; or MDD patients with or without suicidal attempt. However, the atrophy level in the left pallidum showed a positive correlation with severity of suicidal risk in MDD patients with suicidal ideation. Local atrophy of the left hippocampus, right caudate, and right pallidum had a positive correlation with total impulsivity. These findings possibly suggest that vulnerability to suicidal attempt can be derived from suicidal ideation combined with depression and impulsivity, related to reduced motivational control.
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