Evidence map›Paper›PMID 31097632›Full record

ArticleHaematologica2020

Loss of RAF kinase inhibitor protein is involved in myelomonocytic differentiation and aggravates RAS-driven myeloid leukemogenesis.

Veronica Caraffini, Olivia Geiger, Angelika Rosenberger, Stefan Hatzl, Bianca Perfler, Johannes L Berg, Clarice Lim, Herbert Strobl, Karl Kashofer, Silvia Schauer and 10 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. A Novel Potent and Selective GCN2 Inhibitor, APL-4098, Has Antileukemic Activity through Dysregulation of Mitochondrial Function.Clinical cancer research : an official journal of the American Association for Cancer Research · 2026
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  12. RAF Kinase Inhibitor Protein in Myeloid Leukemogenesis.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 3 countries.

Veronica CaraffiniDivision of Hematology, Medical University of Graz, Graz, Austria.
Olivia GeigerDivision of Hematology, Medical University of Graz, Graz, Austria.
Angelika RosenbergerDivision of Hematology, Medical University of Graz, Graz, Austria.
Stefan HatzlDivision of Hematology, Medical University of Graz, Graz, Austria.
Bianca PerflerDivision of Hematology, Medical University of Graz, Graz, Austria.
Johannes L BergDivision of Hematology, Medical University of Graz, Graz, Austria.
Clarice LimOtto Loewi Research Center, Immunology and Pathophysiology, Medical University of Graz, Graz, Austria.
Herbert StroblOtto Loewi Research Center, Immunology and Pathophysiology, Medical University of Graz, Graz, Austria.
Karl KashoferDiagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Silvia SchauerDiagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Christine Beham-SchmidDiagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Gerald HoeflerDiagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Klaus Geissler5 Medical Department with Hematology, Oncology and Palliative Medicine, Hospital Hietzing, Vienna, Austria.
Franz QuehenbergerInstitute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
Walter KolchSystems Biology Ireland and Conway Institute, University College Dublin, Dublin, Ireland.
Dimitris AthineosCancer Research UK Beatson Institute, Glasgow, UK.
Karen BlythCancer Research UK Beatson Institute, Glasgow, UK.
Albert WölflerDivision of Hematology, Medical University of Graz, Graz, Austria.
Heinz SillDivision of Hematology, Medical University of Graz, Graz, Austria.
Armin ZebischDivision of Hematology, Medical University of Graz, Graz, Austria armin.zebisch@medunigraz.at.
Medical University of Graz · ATCancer Research UK Scotland Institute · GBKlinik Hietzing · ATUniversity College Dublin · IE

Funding

Austrian Science Fund FWF P 26619Cancer Research UK 29799
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leukemia, Myeloid, AcutePhosphatidylethanolamine Binding ProteinAnimalsCell DifferentiationMiceMonocytesSignal TransductionPhosphatidylethanolamine Binding ProteinRaf kinase inhibitory protein, mouse

Identifiers

PMID31097632
PMCPMC7012480
OpenAlexW2945220388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.