Evidence map›Paper›PMID 31097584›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock.

Takahiro N Uehara, Yoshiyuki Mizutani, Keiko Kuwata, Tsuyoshi Hirota, Ayato Sato, Junya Mizoi, Saori Takao, Hiromi Matsuo, Takamasa Suzuki, Shogo Ito and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
23.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 107 citations in OpenAlex.

  1. Plant signaling & behavior · 2026
    Article
  2. Article
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  4. Review
  5. Article
  6. Molecular genetic characterization ofbioRxiv : the preprint server for biology · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Circadian gating: concepts, processes, and opportunities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 2 countries.

Takahiro N UeharaDepartment of Chemistry, Graduate School of Science, Nagoya University, 464-8602 Nagoya, Japan.
Yoshiyuki MizutaniDivision of Biological Science, Graduate School of Science, Nagoya University, 464-8602 Nagoya, Japan.
Keiko KuwataInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Tsuyoshi HirotaInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Ayato SatoInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Junya MizoiDepartment of Applied Biological Chemistry, Graduate School of Life and Agricultural Sciences, The University of Tokyo, 113-8657 Tokyo, Japan.
Saori TakaoInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Hiromi MatsuoInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Takamasa SuzukiCollege of Bioscience and Biotechnology, Chubu University, 487-8501 Kasugai, Japan.
Shogo ItoDepartment of Botany, Graduate School of Science, Kyoto University, 606-8502 Kyoto, Japan.
Ami N SaitoDepartment of Applied Chemistry, Waseda University, 169-8555 Tokyo, Japan.
Taeko Nishiwaki-OhkawaInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.
Kazuko Yamaguchi-ShinozakiDepartment of Applied Biological Chemistry, Graduate School of Life and Agricultural Sciences, The University of Tokyo, 113-8657 Tokyo, Japan.
Takashi YoshimuraInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.ORCID 0000-0001-7018-9652
Steve A KayInstitute of Transformative Bio-Molecules, Nagoya University, 464-8601 Nagoya, Japan.ORCID 0000-0002-0402-2878
Kenichiro ItamiDepartment of Chemistry, Graduate School of Science, Nagoya University, 464-8602 Nagoya, Japan.
Toshinori KinoshitaDivision of Biological Science, Graduate School of Science, Nagoya University, 464-8602 Nagoya, Japan.
Junichiro YamaguchiDepartment of Applied Chemistry, Waseda University, 169-8555 Tokyo, Japan; junyamaguchi@waseda.jp nnakamichi@itbm.nagoya-u.ac.jp.
Norihito NakamichiDivision of Biological Science, Graduate School of Science, Nagoya University, 464-8602 Nagoya, Japan; junyamaguchi@waseda.jp nnakamichi@itbm.nagoya-u.ac.jp.
Nagoya University · JPThe University of Tokyo · JPWaseda University · JPChubu University · JPJapan Science and Technology Agency · JPKyoto University · JPUniversity of Southern California · US

Funding

Molecular Mechanisms in the Arabidopsis Circadian ClockR01GM067837 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAY, STEVE A · 2003 to 2015
$4.7M
Molecular Mechanisms in the Arabidopsis Circadian ClockR37GM067837 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STEVE A KAY · 2017 to 2026
$4.4M
NIGMS NIH HHS R01 GM067837NIGMS NIH HHS R37 GM067837
6 · The paper itself

Abstract

The circadian clock provides organisms with the ability to adapt to daily and seasonal cycles. Eukaryotic clocks mostly rely on lineage-specific transcriptional-translational feedback loops (TTFLs). Posttranslational modifications are also crucial for clock functions in fungi and animals, but the posttranslational modifications that affect the plant clock are less understood. Here, using chemical biology strategies, we show that the

Indexed as

ArabidopsisArabidopsis ProteinsCasein Kinase ICircadian ClocksCircadian RhythmGene Expression Regulation, PlantPhosphorylationProtein Processing, Post-TranslationalTranscription FactorsTranscription, GeneticArabidopsis ProteinsCasein Kinase IPRR5 protein, ArabidopsisTOC1 protein, ArabidopsisTranscription FactorsArabidopsiscircadian clockposttranslational regulationsmall molecule

Identifiers

PMID31097584
PMCPMC6561244
OpenAlexW2945175348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.