Evidence map›Paper›PMID 31096980›Full record

ArticleBMC dermatology2019

Sofosbuvir induced leucocytoclasic vasculitis: a case report.

Elena Campione, Annunziata Dattola, Monia Di Prete, Daniele Di Paolo, Amedeo Ferlosio, Augusto Orlandi, Luca Bianchi

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Elena CampioneDepartment of Dermatology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy. campioneelena@hotmail.com.
Annunziata DattolaDepartment of Dermatology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy.
Monia Di PreteDepartment of Anatomic Pathology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy.
Daniele Di PaoloHepatology Unit, Department of Internal Medicine, Rome, Italy.
Amedeo FerlosioDepartment of Anatomic Pathology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy.
Augusto OrlandiDepartment of Anatomic Pathology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy.
Luca BianchiDepartment of Dermatology, University of Rome Tor Vergata, Viale Oxford, 81, 00133, Rome, Italy.
University of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe a case of leucocytoclasic vasculitis induced by Sofosbuvir and its disappearence after the end of the therapy. The hepatitis C virus, firstly described in 1989, is a major global health problem, with high morbidity and mortality. We observed a temporal relationship between the treatment and the onset of vasculitis. We emphasize the multidisciplinary approach to the patients with liver disease to improve the quality of life of these patients. CASE PRESENTATION: A 53-year-old Caucasian man with a history of hepatitis C virus genotype 1 infection was examined at our Department of Dermatology for the occurrence of palpable purpura. The patient referred that the first appearance of the dermatoses was about one month after initiation of therapy with Sofosbuvir for hepatitis C.

conclusionsVasculitis appeared after the beginning of Sofosbuvir and, even though it was treated with different medications proved to be effective, it disappeared only after the conclusion of the therapy, giving a strong evidence to be a drug eruption.

Indexed as

Antiviral AgentsDrug EruptionsHepatitis CHumansMaleMiddle AgedSkinSofosbuvirVasculitis, Leukocytoclastic, CutaneousAntiviral AgentsSofosbuvirHepatitis CLeukocytoclasic vasculitisSofosbuvir

Identifiers

PMID31096980
PMCPMC6524249
OpenAlexW2947639392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.