ArticleBMC veterinary research2019
Determination of the sensitivity and specificity of bovine tuberculosis screening tests in dairy herds in Thailand using a Bayesian approach.
Article in BMC veterinary research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 34 citations in OpenAlex.
- Comparative performance and age dependence of tuberculin and defined antigen bovine tuberculosis skin tests assessed with Bayesian latent class analysis.Scientific reports · 2025Article
- Knowledge, Attitudes, and Practices of Thai Slaughterhouse Personnel Regarding Bovine Tuberculosis Surveillance: A Multi-Regional One Health Assessment.Veterinary sciences · 2025Article
- Comparative analysis of tuberculin and defined antigen skin tests for detection of bovine tuberculosis in buffaloes (Bubalus bubalis) in Haryana state, India.BMC veterinary research · 2024Article
- An ELISA test using a circulatingFrontiers in veterinary science · 2024Article
- Persistence of passive immunity in calves receiving colostrum from cows vaccinated with a live attenuated lumpy skin disease vaccine and the performance of serological tests.Frontiers in veterinary science · 2024Article
- Gamma-interferon assay for the ancillary diagnosis of bovine tuberculosis in dairy cattle in urban and adjacent areas of Dhaka city, Bangladesh.Veterinary world · 2023Article
- Evaluation of the performance of the IFN-γ release assay in bovine tuberculosis free herds from five European countries.Veterinary research · 2023Article
- Development of Nonstructural Protein-Based Indirect ELISA to Identify Elephant Endotheliotropic Herpesvirus (EEHV) Infection in Asian Elephants (Animals : an open access journal from MDPI · 2022Article
- Performance of Loop-Mediated Isothermal Amplification Technique in Milk Samples for the Diagnosis of Bovine Tuberculosis in Dairy Cattle Using a Bayesian Approach.Pathogens (Basel, Switzerland) · 2022Article
- Prevalence, Risk Factors, and Diagnostic Efficacy of Bovine Tuberculosis in Slaughtered Animals at the Chiang Mai Municipal Abattoir, Thailand.Frontiers in veterinary science · 2022Article
- Bayesian Estimation of Diagnostic Accuracy of Three Diagnostic Tests for Bovine Tuberculosis in Egyptian Dairy Cattle Using Latent Class Models.Veterinary sciences · 2021Article
- Study on supplemental test to improve the detection of bovine tuberculosis in individual animals and herds.BMC veterinary research · 2021Article
- Estimates of the global and continental burden of animal tuberculosis in key livestock species worldwide: A meta-analysis study.One health (Amsterdam, Netherlands) · 2020Review
- Validation of a Novel ELISA for the Diagnosis of Hemorrhagic Septicemia in Dairy Cattle from Thailand Using a Bayesian Approach.Veterinary sciences · 2020Article
- Evaluation of an in-house indirect enzyme-linked immunosorbent assay of feline panleukopenia VP2 subunit antigen in comparison to hemagglutination inhibition assay to monitor tiger antibody levels by Bayesian approach.BMC veterinary research · 2020Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objective of this study was to determine the sensitivity (Se) and specificity (Sp) of bovine tuberculosis (bTB) screening tests including a single intradermal tuberculin (SIT) test, interferon gamma (IFN-γ) assay, and a commercial ELISA test (M. bovis Ab) in dairy cattle, under field conditions, using a Bayesian approach.
resultsThe study population consisted of 128 dairy cows from 25 bTB-infected herds in Chiang Mai and Chiang Rai provinces, Thailand. A single-population Bayesian model was implemented assuming conditional dependence between the SIT test and IFN-γ assays. The 95% posterior probability interval (PPI) of the SIT test (severe interpretation) Se ranged from 75.3 to 95.2% (median = 87.6%), while the Sp was slightly lower (median = 83.6%, PPI = 74.2-92.8%). The IFN-γ assay Se was moderate and the 95% PPI ranged from 38.6 to 74.4% (median = 55.7%) with higher Sp (median = 93.5.4%, PPI = 87.0-98.1%). The M. bovis Ab ELISA Se was low, with 95% PPI ranging between 30.0 and 71.2% (median = 47.4%); however, the Sp was high (median = 90.9%, PPI = 84.5-95.5%).
conclusionThe SIT test sensitivity was similar to that demonstrated in other regions and can, therefore, be used effectively as part of control programs in this area. The IFN-γ and M. bovis Ab ELISA assays can be applied as supplementary techniques. The test performance of these tests when used as single tests without confirmation, however, are expected to continue to challenge disease eradication efforts.
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