Evidence map›Paper›PMID 31096640›Full record

ArticleMolecules (Basel, Switzerland)2019

Solid-Phase Synthesis of Phosphorothioate/Phosphonothioate and Phosphoramidate/Phosphonamidate Oligonucleotides.

Ondřej Kostov, Radek Liboska, Ondřej Páv, Pavel Novák, Ivan Rosenberg

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ondřej KostovInstitute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. kostov@uochb.cas.cz.
Radek LiboskaInstitute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. liboska@uochb.cas.cz.
Ondřej PávInstitute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. pav@uochb.cas.cz.
Pavel NovákInstitute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. pavel.novak@uochb.cas.cz.
Ivan RosenbergInstitute of Organic Chemistry and Biochemistry AS CR, v.v.i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic. rosenberg@uochb.cas.cz.
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZ

Funding

Grantová Agentura České Republiky 17-12703S
6 · The paper itself

Abstract

We have developed a robust solid-phase protocol which allowed the synthesis of chimeric oligonucleotides modified with phosphodiester and

Indexed as

Solid-Phase Synthesis TechniquesAmidesDimerizationMolecular StructureOligonucleotidesPhosphatesPhosphoric AcidsPhosphorothioate OligonucleotidesAmidesOligonucleotidesPhosphatesphosphoramidic acidPhosphoric Acidsphosphorodithioic acidPhosphorothioate OligonucleotidesH-phosphinateH-phosphonateoligonucleotidephosphonamidatephosphonatephosphonothioatephosphoramidatephosphoramiditephosphorothioate

Identifiers

PMID31096640
PMCPMC6571627
OpenAlexW2946554962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.