Evidence map›Paper›PMID 31096573›Full record

ReviewNutrients2019

Role of Berry Anthocyanins and Phenolic Acids on Cell Migration and Angiogenesis: An Updated Overview.

Panagiotis Tsakiroglou, Natalie E VandenAkker, Cristian Del Bo', Patrizia Riso, Dorothy Klimis-Zacas

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Arazá:Foods (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Potential Benefits of Black Chokeberry (Molecules (Basel, Switzerland) · 2022
    Review
  9. Review
  10. Review
  11. Article
  12. Oxidative medicine and cellular longevity · 2020
    Article
  13. Phenolic Antioxidants in Aerial Parts of WildAntioxidants (Basel, Switzerland) · 2019
    Review
  14. QSAR studies of the antioxidant activity of anthocyanins.Journal of food science and technology · 2019
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Panagiotis TsakiroglouSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA. panagiotis.tsakiroglou@maine.edu.ORCID 0000-0001-8823-9507
Natalie E VandenAkkerSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA. natalie.marchi@maine.edu.
Cristian Del Bo'Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20123 Milan, Italy. cristian.delbo@unimi.it.ORCID 0000-0001-7562-377X
Patrizia RisoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), Università degli Studi di Milano, 20123 Milan, Italy. patrizia.riso@unimi.it.ORCID 0000-0002-9204-7257
Dorothy Klimis-ZacasSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA. dorothea@maine.edu.
University of Maine · USUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell migration is a critical process that is highly involved with normal and pathological conditions such as angiogenesis and wound healing. Important members of the RHO GTPase family are capable of controlling cytoskeleton conformation and altering motility characteristics of cells. There is a well-known relationship between small GTPases and the PI3K/AKT pathway. Endothelial cell migration can lead to angiogenesis, which is highly linked to wound healing processes. Phenolics, flavonoids, and anthocyanins are major groups of phytochemicals and are abundant in many natural products. Their antioxidant, antimicrobial, anti-inflammatory, antidiabetic, angiogenenic, neuroprotective, hepatoprotective, and cardioprotective properties have been extensively documented. This comprehensive review focuses on the in vitro and in vivo role of berry extracts and single anthocyanin and phenolic acid compounds on cell migration and angiogenesis. We aim to summarize the most recent published studies focusing on the experimental model, type of berry extract, source, dose/concentration and overall effect(s) of berry extracts, anthocyanins, and phenolic acids on the above processes.

Indexed as

AnimalsAnthocyaninsCell MovementFruitHumansNeovascularization, PhysiologicPhytochemicalsAnthocyaninsPhytochemicalsangiogenesisanthocyaninsberriescell migrationextractsHUVECsphenolic acidspolyphenols

Identifiers

PMID31096573
PMCPMC6566276
OpenAlexW2944920365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.