Evidence map›Paper›PMID 31096565›Full record

ArticleInternational journal of molecular sciences2019

In Vitro Study of the Anticancer Effects of Biotechnological Extracts of the Endangered Plant Species

Abbas Khojasteh, Isidoro Metón, Sergio Camino, Rosa M Cusido, Regine Eibl, Javier Palazon

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
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  6. Phytoconstituents and Bioactivity of Plants of the GenusInternational journal of molecular sciences · 2021
    Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Abbas KhojastehSecció de Fisiologia i Biotecnologia Vegetal, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Joan XXIII 27-31, 08028 Barcelona, Spain. abbaskhojasteh@aol.com.
Isidoro MetónSecció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Joan XXIII 27-31, 08028 Barcelona, Spain. imeton@ub.edu.ORCID 0000-0003-2301-2365
Sergio CaminoSecció de Bioquímica i Biologia Molecular, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Joan XXIII 27-31, 08028 Barcelona, Spain. scamino93@gmail.com.
Rosa M CusidoSecció de Fisiologia i Biotecnologia Vegetal, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Joan XXIII 27-31, 08028 Barcelona, Spain. rcusido@ub.edu.
Regine EiblInstitute of Chemistry and Biotechnology, Biochemical Engineering and Cell Cultivation Techniques, Campus Grüental, Zurich University of Applied Sciences, 8820 Wädenswill, Switzerland. eibs@zhaw.ch.
Javier PalazonSecció de Fisiologia i Biotecnologia Vegetal, Departament de Biologia, Sanitat i Medi Ambient, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona, Joan XXIII 27-31, 08028 Barcelona, Spain. javierpalazon@ub.edu.
Universitat de Barcelona · ESZHAW Zurich University of Applied Sciences · CH

Funding

Generalitat de Catalunya BIO2017-82374-RSpanish Ministerio de Ciencia, Innovación y Universidades and AEI/FEDER, EU. BIO2017-82374-R
6 · The paper itself

Abstract

Many medicinal plant species are currently threatened in their natural habitats because of the growing demand for phytochemicals worldwide. A sustainable alternative for the production of bioactive plant compounds are plant biofactories based on cell cultures and organs. In addition, plant extracts from biofactories have significant advantages over those obtained from plants, since they are free of contamination by microorganisms, herbicides and pesticides, and they provide more stable levels of active ingredients. In this context, we report the establishment of

Indexed as

Endangered SpeciesAdenocarcinomaAziridinesBioreactorsCaspase 8CaspasesCell Culture TechniquesCell Cycle CheckpointsCell Line, TumorCell SurvivalCinnamatesCyclohexenesDepsidesHep G2 CellsHumansMCF-7 Cells2,5-diaziridinyl-3-hydroxymethyl-6-methyl-cyclohexa-2,5-diene-1,4-dioneAziridinesCaspase 8CaspasesCinnamatesCyclohexenesDepsidesPhytochemicalsPlant ExtractsRosmarinic AcidcoronatineHepG2 human hepatoma cellsMCF-7 human breast adenocarcinoma cellsplant cell culturesrosmarinic acidSatureja khuzistanica

Identifiers

PMID31096565
PMCPMC6566673
OpenAlexW2945438651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.