ArticleMedicine2019
Association between outdoor air pollution and semen quality: Protocol for an updated systematic review and meta-analysis.
Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impacts of Outdoor Air Pollution on Human Semen Quality: A Meta-Analysis and Systematic Review.BioMed research international · 2020Pooled it
- Advances in Molecular Biology and Immunology of Spermatozoa and Fertilization in Domestic Animals: Implications for Infertility and Assisted Reproduction.Current molecular medicine · 2025Review
- Urban air quality changes resulting from the lockdown period due to the COVID-19 pandemic.International journal of environmental science and technology : IJEST · 2023Article
- Impact of environmental toxin exposure on male fertility potential.Translational andrology and urology · 2020Review
- Will male semen quality improve with environmental quality?Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious studies have explored the association between outdoor air pollution and semen quality. However, the results were still controversial. The object of the current meta-analysis is to evaluate the role of outdoor air pollution in semen quality.
methodsDatabases including PubMed, Web of Science, and Embase will be searched to identify qualified studies. All qualified cross-sectional studies researching the association between outdoor air pollution and sperm parameters will be included. Relative data in participants under higher exposure and lower exposure to air pollution will be extracted by 2 investigators independently. Only participants under the highest and the lowest exposure will be enrolled if the original study contained more than 2 exposure levels. The semen volume, sperm concentration, progressive motility, total motility, and normal morphology rate will be the primary outcomes of the current study. Pooled estimates with corresponding 95% confidence intervals will be calculated to assess the specific effects of outdoor air pollution in semen quality. Moreover, trial sequential analyses will be performed to obtain a more comprehensive assessment of analyses.
resultsA high-quality synthesis of the current evidence for the association between sperm parameters and outdoor air pollution will be provided.
conclusionsThis meta-analysis and systematic review will generate evidence for judging whether outdoor air pollution can impair semen quality. PROSPERO REGISTRATION NUMBER: PROSPERO CRD 42019126060.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.