Evidence map›Paper›PMID 31096520›Full record

SynthesisMedicine2019

Efficacy of traditional Chinese medicine for chronic gastritis: A meta-analysis of randomized controlled trials.

Zi-Xing Yan, Yun-Kai Dai, Teng Ma, Xiao-Ying Lin, Wen-Hui Chen, You-Mei Liu, Ruo-Zhen Zu, Xiao-Bin Zhang, Peng Jiang, Jian-Hua Yang and 3 more

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zi-Xing YanDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Yun-Kai DaiInstitute of Gastroenterology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong.
Teng MaDepartment of Traditional Chinese Medicine, Ningxia People's Hospital, Yinchuan, Ningxia.
Xiao-Ying LinDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Wen-Hui ChenDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
You-Mei LiuDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Ruo-Zhen ZuDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Xiao-Bin ZhangThe First Clinical College, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Peng JiangThe First Clinical College, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Jian-Hua YangThe First Clinical College, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Sheng LiDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Li-Sheng ZhengDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.
Zhen-Wen LinDepartment of Gastroenterology, Affiliated Fuzhou Hospital of Traditional Chinese Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo systematically evaluate efficacy of traditional Chinese medicine (TCM) in treating chronic gastritis (CG).

methodsData sources from PubMed, Embase, Springer Link, China National Knowledge Infrastructure, Chinese Scientific Journals Database, Chinese Biomedicine Database, and Wan-fang database were searched up to July 5, 2018. Review Manager software version 5.3, the Cochrane Collaboration's risk of bias tool, and the Grading of Recommendations Assessment, Development, and Evaluation profiler software were conducted for this meta-analysis.

resultsSixteen studies involving 1673 participants (906 vs 767) were included in this study. Pooled data showed significant statistical differences between TCM groups and current routine pharmacotherapy (RP) groups in overall clinical efficacy (odds ratio [OR] 4.65; 95% confidence interval [CI] 3.29, 6.56; P < .00001), efficacy under endoscopy (OR 2.46; 95% CI 1.12, 5.43; P = .03), stomach distension (mean difference [MD] -0.37; 95% CI -0.56, -0.19; P < .0001), stomachache (standardized MD [SMD] -0.80; 95% CI -1.45, -0.14; P = .02), and belching (SMD -2.00; 95% CI -3.80, -0.20; P = .03). However, acid regurgitation (SMD -0.71; 95% CI -1.69, 0.28; P = .16) and anorexia (SMD -0.75; 95% CI -2.30, 0.80; P = .35) showed no significant statistical differences between 2 groups. In addition, incidence of adverse reactions of TCM groups was lower than that of RP groups.

conclusionEvidence from this meta-analysis suggests that TCM could be more efficacious than current RP in treating CG. But further standardized research of rigorous design should be needed to further validate its efficacy.

Indexed as

AdolescentAdultAgedAged, 80 and overChinaChronic DiseaseEndoscopy, Digestive SystemGastric MucosaGastritisHumansMedicine, Chinese TraditionalMiddle AgedRandomized Controlled Trials as TopicTreatment OutcomeYoung Adult

Identifiers

PMID31096520
PMCPMC6531175

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.