Evidence map›Paper›PMID 31095740›Full record

ArticleThe Laryngoscope2020

The impact of the multidisciplinary tumor board on head and neck cancer outcomes.

Jeffrey C Liu, Adam Kaplon, Elizabeth Blackman, Curtis Miyamoto, Deric Savior, Camille Ragin

Open access · hybridAbstract read
In one paragraph

Article in The Laryngoscope, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Sodium-hyaluronate mouthwash on radiotherapy-induced xerostomia: a randomised clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  3. Article
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Recommendations for the management of cutaneous squamous cell carcinoma: a systematic multidisciplinary Delphi consensus approach.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  9. Observational
  10. Article
  11. Article
  12. Integrating MDT Tumor Board Shadowing into the Undergraduate Medical Curriculum: Perspective of Medical Students.Journal of cancer education : the official journal of the American Association for Cancer Education · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Late laryngeal dysfunction in head and neck cancer survivors.Laryngoscope investigative otolaryngology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeffrey C LiuDepartment of Otolaryngology-Head & Neck Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, U.S.A.
Adam KaplonDepartment of Otolaryngology-Head & Neck Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, U.S.A.ORCID 0000-0003-0873-4722
Elizabeth BlackmanCancer Prevention and Control Research Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, U.S.A.
Curtis MiyamotoDepartment of Radiation Oncology, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, U.S.A.
Deric SaviorDepartment of Medical Oncology, Fox Chase Cancer Center at Temple University Hospital, Philadelphia, Pennsylvania, U.S.A.
Camille RaginCancer Prevention and Control Research Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania, U.S.A.
Fox Chase Cancer Center · USTemple University · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
Investigating genetic ancestry influences on oral cavity and laryngeal cancer survival disparitiesR01CA238061 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI RAGIN, CAMILLE C., SOBOL, ROBERT W · 2019 to 2023
$3.4M
NCI NIH HHS P30 CA006927NCI NIH HHS R01 CA238061
6 · The paper itself

Abstract

objectives/hypothesisAlthough the multidisciplinary tumor board (MTB) is accepted as best practice for the management of head and neck squamous cell carcinoma (HNSCC), there is limited evidence showing its impact on survival. Our goal was to investigate the impact of an MTB following the hiring of a fellowship-trained head and neck surgeon and implementation of an MTB at our institution. We hypothesized that these changes would demonstrate an improvement in survival. STUDY

designRetrospective chart review.

methodsA review of HNSCC treated at our institution between October 2006 and May 2015 was performed. The cohort was divided into pre-MTB (October 2006-February 2011) and post-MTB (February 2011-May 2015) cohorts. Patient demographics, cancer stage, and treatment outcomes were reviewed. Univariate, multivariate, and survival analysis were performed.

resultsThe study included 224 patients, 98 in the pre-MTB cohort and 126 in the post-MTB cohort. Of total patients, 139 (62%) were black and 91 (40%) were on Medicaid or uninsured. Average follow-up time was 2.8 years, and most cases were advanced stage (68%). On Kaplan-Meier evaluation, overall survival and disease-specific survival were significantly improved in the post-MTB cohort compared with the pre-MTB cohort, with a 5-year disease-specific survival of 52% vs. 75% (P = .003). A matched cohort analysis showed that the post-MTB cohort had significantly lower risk of death (hazard ratio: 0.48).

conclusionsOur study demonstrates that treatment of HNSCC by a dedicated multidisciplinary team results in improved survival. Multidisciplinary care should be considered best practice in the care of HNSCC. LEVEL OF EVIDENCE: 3b Laryngoscope, 130:946-950, 2020.

Indexed as

Neoplasm StagingAdultAgedAged, 80 and overCombined Modality TherapyDisease-Free SurvivalFemaleFollow-Up StudiesHead and Neck NeoplasmsHumansMaleMiddle AgedPrognosisRetrospective StudiesSquamous Cell Carcinoma of Head and NeckSurvival Ratecancer survivalHead and neck neoplasmmultidisciplinary tumor boardsquamous cell carcinoma

Identifiers

PMID31095740
PMCPMC7868105
OpenAlexW2946256057

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.