Evidence map›Paper›PMID 31095635›Full record

ArticlePloS one2019

Validity of WHO's near-miss approach in a high maternal mortality setting.

Tanneke Herklots, Lieke van Acht, Rashid Saleh Khamis, Tarek Meguid, Arie Franx, Benoit Jacod

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Indicators for maternal near miss: an observational study, India.Bulletin of the World Health Organization · 2022
    Observational
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tanneke HerklotsDivision of Woman and Baby, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0003-4513-0063
Lieke van AchtDivision of Woman and Baby, University Medical Centre Utrecht, Utrecht, The Netherlands.
Rashid Saleh KhamisDepartment of Obstetrics and Gynaecology, Mnazi Mmoja Hospital, Stone Town, Zanzibar, United Republic of Tanzania.
Tarek MeguidDepartment of Obstetrics and Gynaecology, Mnazi Mmoja Hospital, Stone Town, Zanzibar, United Republic of Tanzania.
Arie FranxDivision of Woman and Baby, University Medical Centre Utrecht, Utrecht, The Netherlands.
Benoit JacodDepartment Obstetrics & Gynaecology, Radboud University Medical Centre, Nijmegen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the validity of WHO's near-miss approach in a low-resource, high maternal mortality setting.

designProspective cohort study.

settingMnazi Mmoja Hospital, the main referral hospital of Zanzibar, Tanzania, from 1 April 2017 until 31 December 2018. POPULATION: All women, pregnant or until 42 days after the end of pregnancy, admitted at Mnazi Mmoja Hospital, the tertiary referral hospital in Zanzibar.

methodsCases of maternal morbidity and mortality were evaluated according to WHO's near-miss approach. The approach's performance was determined by calculating its accuracy through sensitivity, specificity and positive and negative likelihood ratios. The approach's validity was assessed with Pearson's correlation coefficient between the number of organ dysfunction markers and risk of mortality. MAIN OUTCOMES MEASURES: Correlation between number of organ dysfunction markers and risk of mortality, sensitivity and specificity.

results26,842 women were included. There were 335 with a severe maternal outcome: 256 maternal near-miss cases and 79 maternal deaths. No signs of organ dysfunction were documented in only 4 of the 79 cases of maternal death. The number of organ dysfunction markers was highly correlated to the risk of mortality with Pearson's correlation coefficient of 0.89.

conclusionsWHO's near-miss approach adequately identifies women at high risk of maternal mortality in Zanzibar's referral hospital. There is a strong correlation between the number of markers of organ dysfunction and mortality risk.

Indexed as

FemaleHumansIncidenceMaternal Health ServicesMaternal MortalityNear Miss, HealthcarePregnancyPregnancy ComplicationsProspective StudiesReproducibility of ResultsTanzaniaWorld Health Organization

Identifiers

PMID31095635
PMCPMC6522045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.