Evidence map›Paper›PMID 31095554›Full record

ArticlePLoS computational biology2019

Securing the future of research computing in the biosciences.

Joanna Leng, Massa Shoura, Tom C B McLeish, Alan N Real, Mariann Hardey, James McCafferty, Neil A Ranson, Sarah A Harris

Abstract readEditorial
In one paragraph

Article in PLoS computational biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanna LengSchool of Computing, University of Leeds, Leeds, United Kingdom.ORCID 0000-0001-9790-162X
Massa ShouraSchool of Pathology, Stanford University, Palo Alto, California, United States of America.ORCID 0000-0003-3278-296X
Tom C B McLeishDepartment of Physics, University of York, York, United Kingdom.
Alan N RealAdvanced Research Computing, University of Durham, Durham, United Kingdom.ORCID 0000-0001-5166-6329
Mariann HardeyAdvanced Research Computing, University of Durham, Durham, United Kingdom.ORCID 0000-0002-1027-0165
James McCaffertyInformation Services Division, UCL, London, United Kingdom.
Neil A RansonAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.
Sarah A HarrisAstbury Centre for Structural and Molecular Biology, University of Leeds, Leeds, United Kingdom.ORCID 0000-0002-2812-1651

Funding

Wellcome Trust 108466Wellcome Trust 108466/Z/15/ZWellcome Trust 208395/Z/17/Z
6 · The paper itself

Abstract

Improvements in technology often drive scientific discovery. Therefore, research requires sustained investment in the latest equipment and training for the researchers who are going to use it. Prioritising and administering infrastructure investment is challenging because future needs are difficult to predict. In the past, highly computationally demanding research was associated primarily with particle physics and astronomy experiments. However, as biology becomes more quantitative and bioscientists generate more and more data, their computational requirements may ultimately exceed those of physical scientists. Computation has always been central to bioinformatics, but now imaging experiments have rapidly growing data processing and storage requirements. There is also an urgent need for new modelling and simulation tools to provide insight and understanding of these biophysical experiments. Bioscience communities must work together to provide the software and skills training needed in their areas. Research-active institutions need to recognise that computation is now vital in many more areas of discovery and create an environment where it can be embraced. The public must also become aware of both the power and limitations of computing, particularly with respect to their health and personal data.

Indexed as

AnimalsComputational BiologyComputer SimulationData CurationHumansModels, BiologicalSoftware

Identifiers

PMID31095554
PMCPMC6521984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.