Evidence map›Paper›PMID 31095459›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

1D network simulations for evaluating regional flow and pressure distributions in healthy and asthmatic human lungs.

Sanghun Choi, Sujin Yoon, Jichan Jeon, Chunrui Zou, Jiwoong Choi, Merryn H Tawhai, Eric A Hoffman, Renishkumar Delvadia, Andrew Babiskin, Ross Walenga and 1 more

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Human lungs fluid mechanics: an overview of current modelling techniques.The European physical journal. E, Soft matter · 2026
    Review
  2. Article
  3. Article
  4. Forward Computational Modeling of Respiratory Airflow.Applied sciences (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Review
  7. Review
  8. Investigating distributions of inhaled aerosols in the lungs of post-COVID-19 clusters through a unified imaging and modeling approach.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2024
    Article
  9. A computed tomography imaging-based subject-specific whole-lung deposition model.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2022
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sanghun ChoiSchool of Mechanical Engineering, Kyungpook National University , Daegu , Republic of Korea.ORCID 0000-0001-5030-0296
Sujin YoonSchool of Mechanical Engineering, Kyungpook National University , Daegu , Republic of Korea.
Jichan JeonSchool of Mechanical Engineering, Kyungpook National University , Daegu , Republic of Korea.
Chunrui ZouDepartment of Mechanical Engineering, University of Iowa , Iowa City, Iowa.
Jiwoong ChoiIIHR-Hydroscience and Engineering, University of Iowa , Iowa City, Iowa.ORCID 0000-0002-7427-2979
Merryn H TawhaiAuckland Bioengineering Institute, University of Auckland , Auckland , New Zealand.
Eric A HoffmanDepartment of Biomedical Engineering, University of Iowa , Iowa City, Iowa.
Renishkumar DelvadiaOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration , Silver Spring, Maryland.
Andrew BabiskinOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration , Silver Spring, Maryland.
Ross WalengaOffice of Research and Standards, Office of Generic Drugs, Center for Drug Evaluation and Research, US Food and Drug Administration , Silver Spring, Maryland.
Ching-Long LinDepartment of Mechanical Engineering, University of Iowa , Iowa City, Iowa.

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Multi-center Structural & Functional Quantitative CT Pulmonary PhenotypingR01HL112986 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 2012 to 2016
$4.6M
An integrative statistics-guided image-based multi-scale lung modelU01HL114494 · NHLBI · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2013 to 2017
$3.1M
Large-Scale Computing and Visualization for Cardiopulmonary ImagingS10RR022421 · NCRR · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2008 to 2008
$474k
FDA HHS U01 FD005837NCRR NIH HHS S10 RR022421NHLBI NIH HHS R01 HL112986NHLBI NIH HHS U01 HL114494NIDDK NIH HHS P30 DK054759NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

This study aimed to introduce a one-dimensional (1D) computational fluid dynamics (CFD) model for airway resistance and lung compliance to examine the relationship between airway resistance, pressure, and regional flow distribution. We employed five healthy and five asthmatic subjects who had dynamic computed tomography (CT) scans (4D CT) along with two static scans at total lung capacity and functional residual capacity. Fractional air-volume change (

Indexed as

AdultAirway ResistanceAsthmaComputer SimulationExhalationFemaleFour-Dimensional Computed TomographyFunctional Residual CapacityHumansHydrodynamicsInhalationLungMaleModels, BiologicalRespirationRespiratory Function Testsairway diameterairway resistanceboundary conditionlung compliancelung hysteresis

Identifiers

PMID31095459
PMCPMC6692748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.