Evidence map›Paper›PMID 31095080›Full record

SynthesisMedicine and science in sports and exercise2019

Sedentary Behavior and Health: Update from the 2018 Physical Activity Guidelines Advisory Committee.

Peter T Katzmarzyk, Kenneth E Powell, John M Jakicic, Richard P Troiano, Katrina Piercy, Bethany Tennant, 2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Medicine and science in sports and exercise, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06592209 (Body Electric), which is not on this map. Cited by 300 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
300citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06592209 nacompletednot on this mapstarted 2023, after this paper: background citation

Body Electric: a Pragmatic Trial Evaluating Movement Breaks As a Public Health Strategy to Mitigate the Harms of Prolonged Sedentary Behavior

TypeinterventionalSponsorColumbia UniversityRan2023 to 2023Enrolled20,217ConditionsSedentary BehaviorArmsSedentary Breaks
3 · Its place in the literature

Who cites it

300 citing papers in PubMed, 12 syntheses or guidelines pooled it.

  1. Effect of breaking up prolonged sitting with physical activity on executive function: a three-level meta-analysis.The international journal of behavioral nutrition and physical activity · 2026
    Pooled it
  2. Metabolic Syndrome and Obesity-related cancer Risk and Survival: An Umbrella Review of Systematic Reviews With Meta-analysis of Observational Studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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240 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter T KatzmarzykPennington Biomedical Research Center, Baton Rouge, LA.
Kenneth E PowellCenters for Disease Control and Prevention, Atlanta, GA.
John M JakicicDepartment of Health and Physical Activity, University of Pittsburgh, Pittsburgh, PA.
Richard P TroianoDivision of Cancer Control and Population Sciences, National Cancer Institute, U.S. Department of Health and Human Services, Rockville, MD.
Katrina PiercyOffice of Disease Prevention and Health Promotion, US Department of Health and Human Services, Rockville, MD.
Bethany TennantICF, Fairfax, VA.
2018 PHYSICAL ACTIVITY GUIDELINES ADVISORY COMMITTEE*

Funding

Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

purposeTo provide an overview of relationships between sedentary behavior and mortality as well as incidence of several noncommunicable diseases and weight status reported in the 2018 Physical Activity Guidelines Advisory Committee Scientific Report (2018 PAGAC Scientific Report), and to update the evidence from recent studies.

methodsEvidence related to sedentary behavior in the 2018 PAGAC Scientific Report was summarized, and a systematic review was undertaken to identify original studies published between January 2017 and February 2018.

resultsThe 2018 PAGAC Scientific Report concluded there was strong evidence that high amounts of sedentary behavior increase the risk for all-cause and cardiovascular disease (CVD) mortality and incident CVD and type 2 diabetes. Moderate evidence indicated sedentary behavior is associated with incident endometrial, colon and lung cancer. Limited evidence suggested sedentary behavior is associated with cancer mortality and weight status. There was strong evidence that the hazardous effects of sedentary behavior are more pronounced in physically inactive people. Evidence was insufficient to determine if bout length or breaks in sedentary behavior are associated with health outcomes. The new literature search yielded seven new studies for all-cause mortality, two for CVD mortality, two for cancer mortality, four for type 2 diabetes, one for weight status, and four for cancer; no new studies were identified for CVD incidence. Results of the new studies supported the conclusions in the 2018 PAGAC Scientific Report.

conclusionsThe results of the updated search add further evidence on the association between sedentary behavior and health. Further research is required on how sex, age, race/ethnicity, socioeconomic status, and weight status may modify associations between sedentary behavior and health outcomes.

Indexed as

Health StatusPractice Guidelines as TopicSedentary BehaviorAdvisory CommitteesCardiovascular DiseasesDiabetes Mellitus, Type 2ExerciseHumansIncidenceMortalityNeoplasmsObesityRisk Reduction Behavior

Identifiers

PMID31095080
PMCPMC6527341

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.