Evidence map›Paper›PMID 31094344›Full record

SynthesisJournal of medical Internet research2019

Design Choices and Trade-Offs in Health Care Blockchain Implementations: Systematic Review.

Odhran O'Donoghue, Anuraag A Vazirani, David Brindley, Edward Meinert

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
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  4. Applications of Blockchain in the Medical Field: Narrative Review.Journal of medical Internet research · 2021
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  10. Review
  11. Review
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  13. Mobile time banking on blockchain system development for community elderly care.Journal of ambient intelligence and humanized computing · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Odhran O'DonoghueMedical School, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-6507-8990
Anuraag A VaziraniMedical School, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-3642-3390
David BrindleyHealthcare Translation Research Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-5166-8583
Edward MeinertHealthcare Translation Research Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.ORCID 0000-0003-2484-3347
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA blockchain is a list of records that uses cryptography to make stored data immutable; their use has recently been proposed for electronic medical record (EMR) systems. This paper details a systematic review of trade-offs in blockchain technologies that are relevant to EMRs. Trade-offs are defined as "a compromise between two desirable but incompatible features."

objectiveThis review's primary research question was: "What are the trade-offs involved in different blockchain designs that are relevant to the creation of blockchain-based electronic medical records systems?"

methodsSeven databases were systematically searched for relevant articles using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Papers published from January 1, 2017 to June 15, 2018 were selected. Quality assessments of papers were performed using the Risk Of Bias In Non-randomized Studies-of Interventions (ROBINS-I) tool and the Critical Assessment Skills Programme (CASP) tool. Database searches identified 2885 articles, of which 15 were ultimately included for analysis.

resultsA total of 17 trade-offs were identified impacting the design, development, and implementation of blockchain systems; these trade-offs are organized into themes, including business, application, data, and technology architecture.

conclusionsThe key findings concluded the following: (1) multiple trade-offs can be managed adaptively to improve EMR utility; (2) multiple trade-offs involve improving the security of blockchain systems at the cost of other features, meaning EMR efficacy highly depends on data protection standards; and (3) multiple trade-offs result in improved blockchain scalability. Consideration of these trade-offs will be important to the specific environment in which electronic medical records are being developed. This review also uses its findings to suggest useful design choices for a hypothetical National Health Service blockchain. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.2196/10994.

Indexed as

BlockchainComputer SecurityElectronic Health RecordsHealth Information ExchangeHumansblockchaindistributed ledger technologyhealth information exchangeinteroperabilityscalability

Identifiers

PMID31094344
PMCPMC6533871
OpenAlexW2931856624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.