ArticleBiomechanics and modeling in mechanobiology2019
Computational modeling of progressive damage and rupture in fibrous biological tissues: application to aortic dissection.
Article in Biomechanics and modeling in mechanobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 63 citations in OpenAlex.
- Computational modeling of tissue damage preceding aortic dissection: a coupled biphasic and reactive viscoelastic framework.Biomechanics and modeling in mechanobiology · 2026Article
- Helical classification of type B aortic dissections.JTCVS structural and endovascular · 2025Article
- A three-dimensional computational study of critical pressures of dissection propagation in the aorta.Biomechanics and modeling in mechanobiology · 2025Article
- Article
- Mechanisms of aortic dissection: From pathological changes to experimental andProgress in materials science · 2025Article
- Hypertension-Induced Biomechanical Modifications in the Aortic Wall and Their Role in Stanford Type B Aortic Dissection.Biomedicines · 2024Article
- Mathematical modeling and numerical simulation of arterial dissection based on a novel surgeon's view.Biomechanics and modeling in mechanobiology · 2023Article
- An image-based approach for the estimation of arterial local stiffnessFrontiers in bioengineering and biotechnology · 2023Article
- An Alternative Digital Image Correlation-Based Experimental Approach to Estimate Fracture Parameters in Fibrous Soft Materials.Materials (Basel, Switzerland) · 2022Article
- Critical Pressure of Intramural Delamination in Aortic Dissection.Annals of biomedical engineering · 2022Article
- Simulating progressive intramural damage leading to aortic dissection using DeepONet: an operator-regression neural network.Journal of the Royal Society, Interface · 2022Article
- A Review on Damage and Rupture Modelling for Soft Tissues.Bioengineering (Basel, Switzerland) · 2022Review
- A framework for incorporating 3D hyperelastic vascular wall models in 1D blood flow simulations.Biomechanics and modeling in mechanobiology · 2021Article
- Differential propensity of dissection along the aorta.Biomechanics and modeling in mechanobiology · 2021Article
- An adaptive finite element model for steerable needles.Biomechanics and modeling in mechanobiology · 2020Article
- Multimodality Imaging-Based Characterization of Regional Material Properties in a Murine Model of Aortic Dissection.Scientific reports · 2020Article
- Modeling lamellar disruption within the aortic wall using a particle-based approach.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
Abstract
This study analyzes the lethal clinical condition of aortic dissections from a numerical point of view. On the basis of previous contributions by Gültekin et al. (Comput Methods Appl Mech Eng 312:542-566, 2016 and 331:23-52, 2018), we apply a holistic geometrical approach to fracture, namely the crack phase-field, which inherits the intrinsic features of gradient damage and variational fracture mechanics. The continuum framework captures anisotropy, is thermodynamically consistent and is based on finite strains. The balance of linear momentum and the crack evolution equation govern the coupled mechanical and phase-field problem. The solution scheme features the robust one-pass operator-splitting algorithm upon temporal and spatial discretizations. Based on experimental data of diseased human thoracic aortic samples, the elastic material parameters are identified followed by a sensitivity analysis of the anisotropic phase-field model. Finally, we simulate an incipient propagation of an aortic dissection within a multi-layered segment of a thoracic aorta that involves a prescribed initial tear. The finite element results demonstrate a severe damage zone around the initial tear and exhibit a rather helical crack pattern, which aligns with the fiber orientation. It is hoped that the current contribution can provide some directions for further investigations of this disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.