Evidence map›Paper›PMID 31093811›Full record

ReviewInternational microbiology : the official journal of the Spanish Society for Microbiology2020

New insights into copper homeostasis in filamentous fungi.

Martzel Antsotegi-Uskola, Ane Markina-Iñarrairaegui, Unai Ugalde

Open access · hybridAbstract readReview
In one paragraph

Review in International microbiology : the official journal of the Spanish Society for Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 58 citations in OpenAlex.

  1. Mycosorption of copper by Aspergillus terreus SJP02: process optimization and underlying mechanism.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Article
  4. Deciphering the role ofMicrobiology spectrum · 2026
    Article
  5. Functional Analysis ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Iron and copper onPeerJ · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Bioreactor as the root cause of the "manganese effect" duringFrontiers in bioengineering and biotechnology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Martzel Antsotegi-UskolaMicrobial Biochemistry Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country, San Sebastian, Spain.
Ane Markina-IñarrairaeguiMicrobial Biochemistry Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country, San Sebastian, Spain.
Unai UgaldeMicrobial Biochemistry Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of the Basque Country, San Sebastian, Spain. unaiona.ugalde@ehu.eus.
University of the Basque Country · ES

Funding

Hezkuntza Saila, Eusko Jaurlaritza (ES) IT599-13
6 · The paper itself

Abstract

Copper is a metal ion that is required as a micronutrient for growth and proliferation. However, copper accumulation generates toxicity by multiple mechanisms, potentially leading to cell death. Due to its toxic nature at high concentrations, different chemical variants of copper have been extensively used as antifungal agents in agriculture and medicine. Most studies on copper homeostasis have been carried out in bacteria, yeast, and mammalian organisms. However, knowledge on filamentous fungi is less well documented. This review summarizes the knowledge gathered in the last few years about copper homeostasis in the filamentous fungi Aspergillus fumigatus and Aspergillus nidulans: The mechanism of action of copper, the uptake and detoxification systems, their regulation at the transcriptional level, and the role of copper homeostasis in fungal pathogenicity are presented.

Indexed as

HomeostasisBiological TransportCell MembraneCopperFungiGene Expression Regulation, FungalMetabolic Detoxication, Phase IVirulence FactorsCopperVirulence FactorsCopperCtrHomeostasisP-type ATPaseTranscription factor

Identifiers

PMID31093811
PMCPMC6981102
OpenAlexW2945092866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.