Evidence map›Paper›PMID 31093559›Full record

ArticleDiagnostic and prognostic research2018

Diagnostic evidence cooperatives: bridging the valley of death in diagnostics development.

Ann Van den Bruel, Gail Hayward

Open access · goldAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostic and prognostic research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 2 countries.

Ann Van den Bruel1NIHR Diagnostic Evidence Cooperative Oxford, Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Primary Care Building, 32 Woodstock Road, Oxford, OX2 6GG UK.ORCID 0000-0001-9012-2009
Gail Hayward1NIHR Diagnostic Evidence Cooperative Oxford, Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Primary Care Building, 32 Woodstock Road, Oxford, OX2 6GG UK.
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnostic tests' impact on patient outcomes and health processes is potentially large, and proper evaluations before widespread adoption are warranted. Such evaluations are challenged by the fact that tests can have multiple purposes, in different clinical pathways, with different roles. BODY: The National Institute for Health Research (NIHR) established four Diagnostic Evidence Cooperatives (DEC) in 2013, across England. The aim of these DECs was to facilitate the development and evaluation of clinically relevant in vitro diagnostics, by offering methodological expertise and access to real-life settings for evaluations in patients. In this commentary, we discuss our experience over the past 4 years.

conclusionThe interaction of industry, researchers, and clinicians has proven to be very worthwhile.

Indexed as

DiagnosisPrimary careResearch and development

Identifiers

PMID31093559
PMCPMC6460518
OpenAlexW2806156903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.