Evidence map›Paper›PMID 31093517›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2019

Radiomics-based convolutional neural network for brain tumor segmentation on multiparametric magnetic resonance imaging.

Prateek Prasanna, Ayush Karnawat, Marwa Ismail, Anant Madabhushi, Pallavi Tiwari

Open access · greenAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Deep learning in precision medicine and focus on glioma.Bioengineering & translational medicine · 2023
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Radiomics in radiation oncology-basics, methods, and limitations.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Prateek PrasannaCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.ORCID https://orcid.org/0000-0002-3068-3573
Ayush KarnawatCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.
Marwa IsmailCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.
Anant MadabhushiCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.ORCID https://orcid.org/0000-0002-5741-0399
Pallavi TiwariCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio, United States.
Case Western Reserve University · USLouis Stokes Cleveland VA Medical Center · US

Funding

Computerized histologic image predictor of cancer outcomeR01CA202752 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FELDMAN, MICHAEL D, GANESAN, SHRIDAR · 2016 to 2020
$3.1M
Quantitative Histomorphometric Risk Classifier (QuHbIC) in HPV + Oropharyngeal CarcinomaR01CA220581 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KOYFMAN, SHLOMO, LEWIS, JAMES · 2018 to 2023
$3.1M
MR Fingerprinting and Computerized Decision Support for Prostate CancerR01CA208236 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GULANI, VIKAS, PONSKY, LEE EVAN · 2017 to 2022
$3.0M
Pathology Image Informatics Platform for visualization, analysis and managementU24CA199374 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI GURCAN, METIN NAFI, MADABHUSHI, ANANT · 2015 to 2019
$2.9M
BIOMEDICAL ENGINEERING RESEARCH FACILITIESC06RR012463 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI KUTINA, KENNETH L · 1997 to 1997
–
BLRD VA I01 BX004121NCI NIH HHS R01 CA202752NCI NIH HHS R01 CA208236NCI NIH HHS R01 CA220581NCI NIH HHS U24 CA199374NCRR NIH HHS C06 RR012463
6 · The paper itself

Abstract

Accurate segmentation of gliomas on routine magnetic resonance image (MRI) scans plays an important role in disease diagnosis, prognosis, and patient treatment planning. We present a fully automated approach, radiomics-based convolutional neural network (RadCNN), for segmenting both high- and low-grade gliomas using multimodal MRI volumes (T1c, T2w, and FLAIR). RadCNN incorporates radiomic texture features (i.e., Haralick, Gabor, and Laws) within DeepMedic [a deep 3-D convolutional neural network (CNN) segmentation framework that uses image intensities; a top performing method in the BraTS 2016 challenge] to further augment the performance of brain tumor subcompartment segmentation. We first identify textural radiomic representations that best separate the different subcompartments [enhancing tumor (ET), whole tumor (WT), and tumor core (TC)] on the training set, and then feed these representations as inputs to the CNN classifier for prediction of different subcompartments. We hypothesize that textural radiomic representations of lesion subcompartments will enhance the separation of subcompartment boundaries, and hence providing these features as inputs to the deep CNN, over and above raw intensity values alone, will improve the subcompartment segmentation. Using a training set of

Indexed as

convolutional neural networkfeature selectiongliomasradiomicssegmentation

Identifiers

PMID31093517
PMCPMC6503346
OpenAlexW2944143322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.