Evidence map›Paper›PMID 31093505›Full record

ArticleBioMed research international2019

The Polymorphism rs17525495 of LTA4H Is Associated with Susceptibility of Crohn's Disease instead of Intestinal Tuberculosis in a Chinese Han Population.

Zi-Qi Yu, Wen-Fei Wang, Chuan-Zhi Zhu, Ke-Hong Zhang, Xin-Chun Chen, Jian-Yong Chen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Zi-Qi YuDepartment of Gastroenterology & Hepatology, Jiangxi Provincial People's Hospital, Nanchang, China.
Wen-Fei WangDepartment of Microbiology and Immunology, Shenzhen University Health Science Center, Shenzhen, China.
Chuan-Zhi ZhuLaboratory of Molecular Biology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Ke-Hong ZhangDepartment of Microbiology and Immunology, Shenzhen University Health Science Center, Shenzhen, China.
Xin-Chun ChenDepartment of Microbiology and Immunology, Shenzhen University Health Science Center, Shenzhen, China.
Jian-Yong ChenDepartment of Gastroenterology & Hepatology, Jiangxi Provincial People's Hospital, Nanchang, China.ORCID 0000-0001-6679-0912
Shenzhen University Health Science Center · CNCapital Medical University · CNJiangxi Provincial People's Hospital · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBecause of the similarity of intestinal tuberculosis and Crohn's disease in disease phenotype, differential diagnosis has always been a clinical problem. Arachidonic acid metabolites play an important role in the inflammatory response of intestinal tuberculosis and Crohn's disease. Recent studies have shown that the polymorphism locus in the promoter region of

methodsAll the study participants were local Han people from Jiangxi Province in the past eleven years. DNA was extracted from the paraffin-embedded specimens or the whole blood. The

resultsThe T-alleles frequency was not significantly increased in patients with intestinal tuberculosis compared with healthy control group (

conclusionsThe T allele of

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseAdultAsian PeopleCrohn DiseaseEpoxide HydrolasesEthnicityFemaleGene FrequencyHumansMaleModels, GeneticPolymorphism, Single NucleotideTuberculosis, GastrointestinalEpoxide Hydrolasesleukotriene A4 hydrolase

Identifiers

PMID31093505
PMCPMC6481108
OpenAlexW2939386402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.